Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone - Wikidata - wikimedia - TriplyDB

Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone

Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone

http://www.wikidata.org/entity/Q34188560

about

The amazing osteocyte In vitro and in vivo approaches to study osteocyte biology The interaction of biological factors with mechanical signals in bone adaptation: recent developments In Vitro Bone Cell Models: Impact of Fluid Shear Stress on Bone Formation Physiological mechanisms and therapeutic potential of bone mechanosensing.Regulation of Wnt/β-catenin signaling within and from osteocytes Notch signaling in osteocytes differentially regulates cancellous and cortical bone remodeling Gene expression responses to mechanical stimulation of mesenchymal stem cells seeded on calcium phosphate cement In situ intracellular calcium oscillations in osteocytes in intact mouse long bones under dynamic mechanical loading.Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways.Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading Lrp5 is not required for the proliferative response of osteoblasts to strain but regulates proliferation and apoptosis in a cell autonomous manner.Bone muscle crosstalk targets muscle regeneration pathway regulated by core circadian transcriptional repressors DEC1 and DEC2.Systems-based identification of temporal processing pathways during bone cell mechanotransduction.In vivo mechanical loading rapidly activates β-catenin signaling in osteocytes through a prostaglandin mediated mechanism.Protein kinase G and focal adhesion kinase converge on Src/Akt/β-catenin signaling module in osteoblast mechanotransduction Beta-Catenin Haplo Insufficient Male Mice Do Not Lose Bone in Response to Hindlimb Unloading.Update on Wnt signaling in bone cell biology and bone disease.Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms.Skeletal muscle secreted factors prevent glucocorticoid-induced osteocyte apoptosis through activation of β-catenin Canonical Notch activation in osteocytes causes osteopetrosis.The Dmp1-SOST Transgene Interacts With and Downregulates the Dmp1-Cre Transgene and the Rosa(Notch) Allele PUFAs, Bone Mineral Density, and Fragility Fracture: Findings from Human Studies Crosstalk between caveolin-1/extracellular signal-regulated kinase (ERK) and β-catenin survival pathways in osteocyte mechanotransduction Role of Epithelium Sodium Channel in Bone Formation.Isolation and Functional Analysis of an Immortalized Murine Cementocyte Cell Line, IDG-CM6 Rac1 and Cdc42 GTPases regulate shear stress-driven β-catenin signaling in osteoblasts.Circulatory shear flow alters the viability and proliferation of circulating colon cancer cells LRP5 and bone mass regulation: Where are we now?The osteocyte: an endocrine cell ... and more.The Influence of the Type of Continuous Exercise Stress Applied during Growth Periods on Bone Metabolism and Osteogenesis.Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis.Fluid flow shear stress over podocytes is increased in the solitary kidney.Reciprocal cross-talk between Prostaglandin E2 and bone in prostate cancer: a current review.Sclerostin's role in bone's adaptive response to mechanical loading.Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement.The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth.Ibuprofen before Exercise Does Not Prevent Cortical Bone Adaptations to Training.Influence of osteocytes in the in vitro and in vivo β-tricalcium phosphate-stimulated osteogenesis.Hyperfiltration-associated biomechanical forces in glomerular injury and response: Potential role for eicosanoids.

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P2860

Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone

http://www.wikidata.org/entity/Q34188560

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Activation of β-catenin signal ...... dy of mechanosensation in bone

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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type

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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Activation of β-catenin signal ...... dy of mechanosensation in bone

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J.BONE.2010.08.007

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Activation of β-catenin signal ...... dy of mechanosensation in bone

@en

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Mark L Johnson

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Mohamed A Kamel

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Nuria Lara-Castillo

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P2860

Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling.

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts.

Mechanotransduction of bone cells in vitro: mechanobiology of bone tissue.

Osteocytes, mechanosensing and Wnt signaling.

Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal.

Gene expression signatures of a fibroblastoid preosteoblast and cuboidal osteoblast cell model compared to the MLO-Y4 osteocyte cell model

Identification of differentially expressed genes between osteoblasts and osteocytes.

Mechanical loading regulates NFATc1 and beta-catenin signaling through a GSK3beta control node.

Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways.

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10.1016/J.BONE.2010.08.007

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5

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47

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20713195

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mechanosensation

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2952691

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