Reduced thrombin binding and aggregation in Bernard-Soulier platelets
about
Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structuresCloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoproteinVariant Bernard-Soulier syndrome type bolzano. A congenital bleeding disorder due to a structural and functional abnormality of the platelet glycoprotein Ib-IX complexIn vivo relevance for platelet glycoprotein Ibalpha residue Tyr276 in thrombus formation.Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the G(i)-independent activation of platelet Rap1B by thrombin.Identification of the thrombin receptor on human platelets by chemical crosslinking.Human neutrophil elastase modulates platelet function by limited proteolysis of membrane glycoproteins.Role of shear rate and platelets in promoting fibrin formation on rabbit subendothelium. Studies utilizing patients with quantitative and qualitative platelet defects.Platelet receptors and their role in diseases.High-affinity alpha-thrombin binding to platelet glycoprotein Ib alpha: identification of two binding domains.Spontaneous platelet aggregation in a hereditary giant platelet syndrome (MPS)The interaction of thrombin with blood platelets.Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activationAnalysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis.Characterization of the platelet membrane glycoprotein abnormalities in Bernard-Soulier syndrome and comparison with normal by surface-labeling techniques and high-resolution two-dimensional gel electrophoresisStructural analysis of human platelet membrane glycoprotein I complex.Nonsense mutation in the glycoprotein Ib alpha coding sequence associated with Bernard-Soulier syndromeNew Concepts and Mechanisms of Platelet Activation Signaling.Technical considerations for platelet aggregation and related problems.Absence of the platelet receptor for drug-dependent antibodies in the Bernard-Soulier syndrome.Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system.A mitogen-activated protein kinase-dependent signaling pathway in the activation of platelet integrin alpha IIbbeta3.Glycoprotein Ib-mediated platelet activation. A signalling pathway triggered by thrombin.A platelet secretion pathway mediated by cGMP-dependent protein kinase.Thrombin-induced platelet aggregation is inhibited by the heptapeptide Leu271-Ala277 of domain 3 in the heavy chain of high molecular weight kininogen.Factor XI binding to the platelet glycoprotein Ib-IX-V complex promotes factor XI activation by thrombin.Epinephrine induces intracellular Ca2+ mobilization in thrombin-desensitized platelets: a role for GPIb-IX-V.Binding of thrombin to the G-protein-linked receptor, and not to glycoprotein Ib, precedes thrombin-mediated platelet activation.
P2860
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P2860
Reduced thrombin binding and aggregation in Bernard-Soulier platelets
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1978
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Reduced thrombin binding and aggregation in Bernard-Soulier platelets
@en
Reduced thrombin binding and aggregation in Bernard-Soulier platelets.
@nl
type
label
Reduced thrombin binding and aggregation in Bernard-Soulier platelets
@en
Reduced thrombin binding and aggregation in Bernard-Soulier platelets.
@nl
prefLabel
Reduced thrombin binding and aggregation in Bernard-Soulier platelets
@en
Reduced thrombin binding and aggregation in Bernard-Soulier platelets.
@nl
P2860
P356
P1476
Reduced thrombin binding and aggregation in Bernard-Soulier platelets
@en
P2093
Jamieson GA
P2860
P304
P356
10.1172/JCI109000
P407
P577
1978-03-01T00:00:00Z