Review on the APP/PS1KI mouse model: intraneuronal Abeta accumulation triggers axonopathy, neuron loss and working memory impairment.
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The toxicity of amyloid β oligomersAge-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis.Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse modelCo-occurrence of Alzheimer's disease ß-amyloid and τ pathologies at synapses.Molecular basis for increased risk for late-onset Alzheimer disease due to the naturally occurring L28P mutation in apolipoprotein E4.An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficitsCeramide and Related-Sphingolipid Levels Are Not Altered in Disease-Associated Brain Regions of APP and APP/PS1 Mouse Models of Alzheimer's Disease: Relationship with the Lack of Neurodegeneration?The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signalingCholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model.Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer's disease.An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines.The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific.Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease.Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?Neurotoxic saboteurs: straws that break the hippo's (hippocampus) back drive cognitive impairment and Alzheimer's Disease.Localization of mature neprilysin in lipid rafts.Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice.Natural non-trasgenic animal models for research in Alzheimer's disease.Glial Draper Rescues Aβ Toxicity in a Drosophila Model of Alzheimer's Disease.Effects of Alzheimer's disease transgenes on neurochemical expression in the mouse brain determined by ¹H MRS in vitro.Gene Expression Profiling in the APP/PS1KI Mouse Model of Familial Alzheimer's Disease.Endogenous Apolipoprotein E (ApoE) Fragmentation Is Linked to Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease.
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P2860
Review on the APP/PS1KI mouse model: intraneuronal Abeta accumulation triggers axonopathy, neuron loss and working memory impairment.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Review on the APP/PS1KI mouse ...... and working memory impairment.
@en
Review on the APP/PS1KI mouse ...... and working memory impairment.
@nl
type
label
Review on the APP/PS1KI mouse ...... and working memory impairment.
@en
Review on the APP/PS1KI mouse ...... and working memory impairment.
@nl
prefLabel
Review on the APP/PS1KI mouse ...... and working memory impairment.
@en
Review on the APP/PS1KI mouse ...... and working memory impairment.
@nl
P2860
P1476
Review on the APP/PS1KI mouse ...... and working memory impairment.
@en
P2093
P2860
P356
10.1111/J.1601-183X.2007.00372.X
P407
P478
P577
2008-02-01T00:00:00Z