about
Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stressOrphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic propertiesIdentification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylasesSRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1Effects of Oxidative Stress on Mesenchymal Stem Cell BiologyThe Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5)Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: INTRACELLULAR -O-LINKED N-GLYCOLYLGLUCOSAMINE (GlcNGc), UDP-GlcNGc, AND THE BIOCHEMICAL AND STRUCTURAL RATIONALE FOR THE SUBSTRATE TOLERANCE OF -O-LINKED -N-ACETYLGLUCOSAMINIDASEEpigenetic polypharmacology: from combination therapy to multitargeted drugsFunction of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative diseaseExpanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pairReactive oxygen species, cellular redox systems, and apoptosisMammalian sirtuins: biological insights and disease relevanceInsights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins.Regulation of histone acetylation in the hippocampus of chronically stressed rats: a potential role of sirtuins.Chemical phylogenetics of histone deacetylases.Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activityAn aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Nitric oxide: perspectives and emerging studies of a well known cytotoxinA novel class of small molecule inhibitors of HDAC6.Biologically active isoforms of CobB sirtuin deacetylase in Salmonella enterica and Erwinia amylovora.Effects of gambogic acid on the activation of caspase-3 and downregulation of SIRT1 in RPMI-8226 multiple myeloma cells via the accumulation of ROS.Epigenetic control of agingSirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.The redox basis of epigenetic modifications: from mechanisms to functional consequences.Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROSBiological targets and mechanisms of action of natural products from marine cyanobacteria.A mechanism-based potent sirtuin inhibitor containing Nε-thiocarbamoyl-lysine (TuAcK)Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases.Sirtuins in neurodegenerative diseases: a biological-chemical perspective.Preclinical studies on histone deacetylase inhibitors as therapeutic reagents for endometrial and ovarian cancers.Function and metabolism of sirtuin metabolite O-acetyl-ADP-riboseQuantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.Butyrate histone deacetylase inhibitors.Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma.MEK1 signaling promotes self-renewal and tumorigenicity of liver cancer stem cells via maintaining SIRT1 protein stabilizationIdentification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coliHistone deacetylases as targets for the treatment of human neurodegenerative diseases.Sirtuin mechanism and inhibition: explored with N(ε)-acetyl-lysine analogs.Regulation of intermediary metabolism by protein acetylation.
P2860
Q24295960-4ABCA28E-9727-4809-AB86-7154A0D1C6E8Q24323173-803BC861-02D7-40A0-B01F-A0BA9368E2CCQ24338022-62FB188C-FA24-401F-A053-2940CC370CE0Q24633063-9F6DDA65-0B83-410D-8F7F-FCB79488D393Q26740408-619475FD-B300-4A78-B9B4-A30BC8010E8DQ27670648-46885269-0EEE-408C-8F8D-55B185B4AEB8Q27681140-63E0151C-0F0D-4442-998B-E68A68ACB20DQ28067666-B4B97BE3-3591-4625-B725-3D825D30C36FQ28068499-BF8ACEB4-ED42-4A19-B532-AA1DF89760E9Q28294964-2E97D441-E286-4D7E-A072-A36BC327A16DQ28393669-CA59E455-D194-4B42-ABDD-D4FC02374F32Q29614496-C56FCD37-7DF8-419F-9F8C-E6E60543A505Q30388525-541A702C-C6BE-4E9A-AE0A-344C85A92C19Q30428450-3859EB62-7DE5-47E6-804A-D851003FD1D1Q30977637-5F6E9B34-F81C-4F7E-ADF4-C286FA8A5013Q33694651-82B29FFB-5FE0-4E2F-B1C7-DD60945ABE3DQ33743418-E1C0561F-CD89-42A3-91FA-F11A407E4931Q34061919-82EB90FC-C3DE-499D-A465-8385432F0DD7Q34065056-850A89A1-E5B4-4418-AD88-7AFFF73D585EQ34309358-24C959B1-81A9-4A77-B5F9-80F5FC4D8F0FQ34333083-92DCD420-1BD7-45FF-B7BC-986AD1832430Q34460981-B31D7028-9314-4BDD-A5CF-106C78B3F126Q35003686-B40F6B61-381F-4DEC-AD5D-E2064BB30958Q35041432-6F6BCDBD-2A51-4235-A640-042A6BD10DADQ35055739-E4C4D97D-AD0F-49CD-B5E5-755DF5D18EE9Q35082662-4E01823F-185E-4565-8222-5FCE3FFB81B2Q35130835-71988B8B-3264-49E7-9064-D1268BC68B57Q35136617-3FD80AD4-05A5-4C33-A125-3AD6DDA81214Q35194759-ED1D2457-23CF-4149-91A0-64CFCE72DDA2Q35661567-2F0B2EB3-0CD8-4108-843B-F888A7788EEFQ35739684-A881AA0D-79F8-4A72-BF30-8994B108556EQ35846790-C66EB44C-5A9C-4D1C-AAAD-4184D85EEC38Q36386750-6E6937A7-CBB3-4FEB-A889-8F4247CF2441Q36574546-71BEB50F-E08D-47C6-ADCA-97CA8D8AB5A7Q36809567-AF22C532-D670-4B35-9B6E-D99D65B94112Q37190384-BB6E5EA9-5AAC-43FC-9964-B8F5CD5328F8Q37388964-95B909F3-E9DD-4CD3-A95F-2F6C85F18477Q37602632-678D4445-81C7-4906-84EF-7E0842A3425BQ37788970-A9DA4288-6244-4FA6-9ECA-495745558FD8Q37799059-75B5B825-745D-44F5-B153-4E14F0091669
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mechanisms and molecular probes of sirtuins.
@en
Mechanisms and molecular probes of sirtuins.
@nl
type
label
Mechanisms and molecular probes of sirtuins.
@en
Mechanisms and molecular probes of sirtuins.
@nl
prefLabel
Mechanisms and molecular probes of sirtuins.
@en
Mechanisms and molecular probes of sirtuins.
@nl
P2860
P1476
Mechanisms and molecular probes of sirtuins
@en
P2093
John M Denu
William C Hallows
P2860
P304
P356
10.1016/J.CHEMBIOL.2008.09.009
P50
P577
2008-10-01T00:00:00Z