Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
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Use of human bronchial epithelial cells (BEAS-2B) to study immunological markers resulting from exposure to PM(2.5) organic extract from Puerto Rico.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Pregnane X receptor-mediated induction of Cyp3a by black cohosh.Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathwaysActivation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines.PXR-Mediated Upregulation of CYP3A Expression by Herb Compound Praeruptorin C from Peucedanum praeruptorum Dunn.Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes.Nonviral gene transfer as a tool for studying transcription regulation of xenobiotic metabolizing enzymes.Pharmacokinetic drug interactions involving Ginkgo biloba.Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study.Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner.Assessment of a pharmacokinetic and pharmacodynamic interaction between simvastatin and Ginkgo biloba extracts in healthy subjects.Hepatotoxicity of Herbal Supplements Mediated by Modulation of Cytochrome P450.The effect of complementary and alternative medicines on CYP3A4-mediated metabolism of three different substrates: 7-benzyloxy-4-trifluoromethyl-coumarin, midazolam and docetaxel.Effects ofGinkgo bilobaextracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices
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Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 August 2008
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
@en
Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
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type
label
Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
@en
Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
@nl
prefLabel
Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
@en
Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
@nl
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Identification of Ginkgo biloba as a novel activator of pregnane X receptor.
@en
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Eugene Y H Yeung
Masahiko Negishi
Tatsuya Sueyoshi
Thomas K H Chang
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P304
P356
10.1124/DMD.108.023499
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2008-08-25T00:00:00Z