St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
about
Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CARIdentification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearanceEffects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazideGauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokineticsModulation of xenobiotic receptors by steroidsTargeting xenobiotic receptors PXR and CAR for metabolic diseasesPolyherbal formulation: Concept of ayurvedaIn vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenograftsCrystal structure of the PXR–T1317 complex provides a scaffold to examine the potential for receptor antagonismIdentification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genesVitamin E in human health and diseaseSaint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposureEnhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alphaBiochemical Mechanisms for Geographical Adaptations to Novel Toxin Exposures in ButterflyfishAlterations of chemotherapeutic pharmacokinetic profiles by drug-drug interactionsPregnane X receptor and natural products: beyond drug-drug interactionsThe Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors.Summary of information on human CYP enzymes: human P450 metabolism data.Pharmacokinetic interactions of drugs with St John's wort.Evaluation of cytotoxic, genotoxic and CYP450 enzymatic competition effects of Tanzanian plant extracts traditionally used for treatment of fungal infections.Clinically relevant safety issues associated with St. John's wort product labels.Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cellsThe phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptorImproving the oral bioavailability of beneficial polyphenols through designed synergies.St. John's Wort Has Metabolically Favorable Effects on Adipocytes In Vivo.The best of both approaches. The role of science in complementary and alternative medicineEffect of Red Clover on CYP Expression: An Investigation of Herb-Drug Interaction at Molecular Level.Hypericum perforatum (St John's Wort): a non-selective reuptake inhibitor? A review of the recent advances in its pharmacology.St. John's Wort enhances the synaptic activity of the nucleus of the solitary tractDexamethasone transcriptionally increases the expression of the pregnane X receptor and synergistically enhances pyrethroid esfenvalerate in the induction of cytochrome P450 3A23.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Regulation of xenobiotic metabolism by orphan nuclear receptors.P-Glycoprotein- and cytochrome P-450-mediated herbal drug interactions.St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties.The influence of standardized Valeriana officinalis extract on the CYP3A1 gene expression by nuclear receptors in in vivo model.Orphan nuclear receptors: the exotics of xenobiotics.Herbal modulation of P-glycoprotein.The Chinese herbal medicine Sophora flavescens activates pregnane X receptorAristoforin, a novel stable derivative of hyperforin, is a potent anticancer agent.Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism.
P2860
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P2860
St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
St. John's wort induces hepati ...... ion of the pregnane X receptor
@ast
St. John's wort induces hepati ...... ion of the pregnane X receptor
@en
St. John's wort induces hepati ...... ion of the pregnane X receptor
@nl
type
label
St. John's wort induces hepati ...... ion of the pregnane X receptor
@ast
St. John's wort induces hepati ...... ion of the pregnane X receptor
@en
St. John's wort induces hepati ...... ion of the pregnane X receptor
@nl
prefLabel
St. John's wort induces hepati ...... ion of the pregnane X receptor
@ast
St. John's wort induces hepati ...... ion of the pregnane X receptor
@en
St. John's wort induces hepati ...... ion of the pregnane X receptor
@nl
P2093
P2860
P3181
P356
P1476
St. John's wort induces hepati ...... ion of the pregnane X receptor
@en
P2093
C J Serabjit-Singh
G B Wisely
J L Collins
S A Kliewer
T M Willson
P2860
P304
P3181
P356
10.1073/PNAS.130155097
P407
P577
2000-06-20T00:00:00Z