Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.
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Teratogenic mechanisms of medical drugsGene expression in the fetal mouse ovary is altered by exposure to low doses of bisphenol AXenotransplantation models to study the effects of toxicants on human fetal tissuesProposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodentsIn utero exposure to di-(2-ethylhexyl) phthalate induces testicular effects in neonatal rats that are antagonized by genistein cotreatmentTranscriptional biomarkers of steroidogenesis and trophoblast differentiation in the placenta in relation to prenatal phthalate exposureDifferential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell functionCadmium increases human fetal germ cell apoptosisMaternal Exposure to Domestic Hair Cosmetics and Occupational Endocrine Disruptors Is Associated with a Higher Risk of Hypospadias in the OffspringNuclear receptors and endocrine disruptors in fetal and neonatal testes: a gapped landscape.Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay.Human fetal testis xenografts are resistant to phthalate-induced endocrine disruption.Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in miceSignaling pathways in spermatogonial stem cells and their disruption by toxicantsProlonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft modelXenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation.Personal care products and endocrine disruption: A critical review of the literature.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.A critical assessment of the endocrine susceptibility of the human testis to phthalates from fetal life to adulthood.Similar causes of various reproductive disorders in early lifeCellular and molecular effect of MEHP Involving LXRα in human fetal testis and ovary.Urinary phthalate metabolites are associated with decreased serum testosterone in men, women, and children from NHANES 2011-2012.Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.Phthalate esters affect maturation and function of primate testis tissue ectopically grafted in miceAn investigation of the endocrine-disruptive effects of bisphenol a in human and rat fetal testes.Comparative effects of di(n-butyl) phthalate exposure on fetal germ cell development in the rat and in human fetal testis xenograftsMan is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetusEffects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.Testicular connexin 43, a precocious molecular target for the effect of environmental toxicants on male fertilityGender-Specific Adverse Effects of Mono-Ethylhexyl Phthalate on Steroidogenesis in Immature Granulosa Cells and Rat Leydig cell Progenitors in vitro.Human Chorionic Gonadotropin Partially Mediates Phthalate Association With Male and Female Anogenital Distance.Retracted article: In vitro derivation of mammalian germ cells from stem cells and their potential therapeutic application.Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent.Associations between paternal urinary phthalate metabolite concentrations and reproductive outcomes among couples seeking fertility treatment.Associations between urinary metabolites of di(2-ethylhexyl) phthalate and reproductive hormones in fertile men.Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro.Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmosetPhthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanismHuman infertility: are endocrine disruptors to blame?The dynamic epigenetic program in male germ cells: Its role in spermatogenesis, testis cancer, and its response to the environment.
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Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Phthalates impair germ cell de ...... ge in testosterone production.
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Phthalates impair germ cell de ...... ge in testosterone production.
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Phthalates impair germ cell de ...... ge in testosterone production.
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Phthalates impair germ cell de ...... ge in testosterone production.
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Phthalates impair germ cell de ...... ge in testosterone production.
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Phthalates impair germ cell de ...... ge in testosterone production.
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P2093
P2860
P356
P1476
Phthalates impair germ cell de ...... nge in testosterone production
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P2093
Catherine Pairault
Delphine Moison
Gaëlle Angenard
Hervé Coffigny
René Frydman
René Habert
Romain Lambrot
Vincent Muczynski
Virginie Rouiller-Fabre
P2860
P356
10.1289/EHP.11146
P577
2008-09-09T00:00:00Z