Developmentally regulated sphingolipid synthesis in African trypanosomes
about
Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma bruceiPhospholipid and sphingolipid metabolism in Leishmania.Life Stage-Specific Cargo Receptors Facilitate Glycosylphosphatidylinositol-Anchored Surface Coat Protein Transport in Trypanosoma brucei.Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.Sphingolipids in parasitic protozoaA novel protein kinase localized to lipid droplets is required for droplet biogenesis in trypanosomes.Surface proteins, ERAD and antigenic variation in Trypanosoma brucei.Amino acid determinants of substrate selectivity in the Trypanosoma brucei sphingolipid synthase family.Replication of the ERES:Golgi junction in bloodstream-form African trypanosomes.Trypanosoma brucei Bloodstream Forms Depend upon Uptake of myo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth.Sphingolipid and ceramide homeostasis: potential therapeutic targets.Identification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis.myo-Inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei.Form and function in the trypanosomal secretory pathway.Flagellar membranes are rich in raft-forming phospholipidsInositolphosphoceramide metabolism in Trypanosoma cruzi as compared with other trypanosomatids.Controlling transferrin receptor trafficking with GPI-valence in bloodstream stage African trypanosomes.Intracellular trafficking and glycobiology of TbPDI2, a stage-specific protein disulfide isomerase in Trypanosoma bruceiMolecular and functional characterization of the ceramide synthase from Trypanosoma cruzi.Inhibition of nucleotide sugar transport in Trypanosoma brucei alters surface glycosylation.A Gene of the β3-Glycosyltransferase Family Encodes N-Acetylglucosaminyltransferase II Function in Trypanosoma bruceiLipidomic analysis of bloodstream and procyclic form Trypanosoma bruceiLipid metabolism in Trypanosoma bruceiFlagellar membrane localization via association with lipid rafts.Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansStreamlined architecture and glycosylphosphatidylinositol-dependent trafficking in the early secretory pathway of African trypanosomes.Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis.State of the art in African trypanosome drug discovery.Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes.Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis.Multiple-stage linear ion-trap with high resolution mass spectrometry towards complete structural characterization of phosphatidylethanolamines containing cyclopropane fatty acyl chain in Leishmania infantum.Lipidomics and anti-trypanosomatid chemotherapy.Depletion of mitochondrial acyl carrier protein in bloodstream-form Trypanosoma brucei causes a kinetoplast segregation defect.Role of AP-1 in developmentally regulated lysosomal trafficking in Trypanosoma brucei.Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase.Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries.The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease.The essential neutral sphingomyelinase is involved in the trafficking of the variant surface glycoprotein in the bloodstream form of Trypanosoma brucei.Exploring Leishmania major inositol phosphorylceramide synthase (LmjIPCS): insights into the ceramide binding domain.Biological network modeling identifies IPCS in Leishmania as a therapeutic target.
P2860
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P2860
Developmentally regulated sphingolipid synthesis in African trypanosomes
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Developmentally regulated sphingolipid synthesis in African trypanosomes
@en
Developmentally regulated sphingolipid synthesis in African trypanosomes.
@nl
type
label
Developmentally regulated sphingolipid synthesis in African trypanosomes
@en
Developmentally regulated sphingolipid synthesis in African trypanosomes.
@nl
prefLabel
Developmentally regulated sphingolipid synthesis in African trypanosomes
@en
Developmentally regulated sphingolipid synthesis in African trypanosomes.
@nl
P2093
P2860
P921
P1476
Developmentally regulated sphingolipid synthesis in African trypanosomes
@en
P2093
Elitza S Sevova
Fong-Fu Hsu
James D Bangs
Kevin J Schwartz
Phillip Key
Shaheen S Sutterwala
P2860
P304
P356
10.1111/J.1365-2958.2008.06393.X
P407
P577
2008-08-11T00:00:00Z