IL-17 contributes to CD4-mediated graft-versus-host disease.
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Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic StrategiesThe Role of Intestinal Microbiota in Acute Graft-versus-Host DiseaseThe Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host DiseaseCurrent data on IL-17 and Th17 cells and implications for graft versus host disease.Heparanase promotes engraftment and prevents graft versus host disease in stem cell transplantationInterleukin 17 is not required for autoimmune-mediated pathologic damage during chronic graft-versus-host diseaseKinetics of IFN-γ and IL-17 Production by CD4 and CD8 T Cells during Acute Graft-versus-Host Disease.Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.TLR signals promote IL-6/IL-17-dependent transplant rejection.An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition.Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse?Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis.SOCS3 regulates graft-versus-host disease.Advances in graft-versus-host disease biology and therapy.Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses.A genetic variant in the IL-17 promoter is functionally associated with acute graft-versus-host disease after unrelated bone marrow transplantation.Development of a T(H)17 immune response during the induction of murine syngeneic graft-versus-host diseaseTh17 immune responses contribute to the pathophysiology of aplastic anemia.Immune regulatory cells in umbilical cord blood and their potential roles in transplantation tolerance.Th17/Treg ratio in human graft-versus-host disease.Decreased levels of circulating IL17-producing CD161+CCR6+ T cells are associated with graft-versus-host disease after allogeneic stem cell transplantation.Dectin-1: a role in antifungal defense and consequences of genetic polymorphisms in humans.Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.Muramyl dipeptide induces Th17 polarization through activation of endothelial cells.Altered effector CD4+ T cell function in IL-21R-/- CD4+ T cell-mediated graft-versus-host diseaseInvestigating the relationship between serum interleukin-17 levels and systemic immune-mediated disease in patients with dry eye syndromeSequential activation of inflammatory signaling pathways during graft-versus-host disease (GVHD): early role for STAT1 and STAT3.Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.Effects of Pre-conditioning Dose on the Immune Kinetics and Cytokine Production in the Leukocytes Infiltrating GVHD Tissues after MHC-matched Transplantation.HDAC inhibition and graft versus host diseaseInterleukin-17 in various ocular surface inflammatory diseasesAbrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVLCD4+ T cell STAT3 phosphorylation precedes acute GVHD, and subsequent Th17 tissue invasion correlates with GVHD severity and therapeutic response.Innate signals overcome acquired TCR signaling pathway regulation and govern the fate of human CD161(hi) CD8α⁺ semi-invariant T cellsIL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effectsPrevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice.Absence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in miceBone marrow and the control of immunity.Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes.Attenuation of acute graft-versus-host disease in the absence of the transcription factor RORγt.
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P2860
IL-17 contributes to CD4-mediated graft-versus-host disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 17 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
IL-17 contributes to CD4-mediated graft-versus-host disease.
@en
IL-17 contributes to CD4-mediated graft-versus-host disease.
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type
label
IL-17 contributes to CD4-mediated graft-versus-host disease.
@en
IL-17 contributes to CD4-mediated graft-versus-host disease.
@nl
prefLabel
IL-17 contributes to CD4-mediated graft-versus-host disease.
@en
IL-17 contributes to CD4-mediated graft-versus-host disease.
@nl
P2093
P2860
P1433
P1476
IL-17 contributes to CD4-mediated graft-versus-host disease.
@en
P2093
Amanda M Holland
Cassandra Ligh
Christopher G King
David Y Suh
Gabrielle L Goldberg
Glenn Heller
Jeremy Grubin
Lucy W Kappel
Marcel R M van den Brink
P2860
P304
P356
10.1182/BLOOD-2008-08-172155
P407
P577
2008-10-17T00:00:00Z