Downregulation of Mcl-1 through inhibition of translation contributes to benzyl isothiocyanate-induced cell cycle arrest and apoptosis in human leukemia cells.
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Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating EnzymesMolecular targets of isothiocyanates in cancer: recent advancesRhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo.EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibitionRapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains.Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulationBenzyl Isothiocyanate Inhibits Prostate Cancer Development in the Transgenic Adenocarcinoma Mouse Prostate (TRAMP) Model, Which Is Associated with the Induction of Cell Cycle G1 Arrest.Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway.Dual inhibition of Mcl-1 by the combination of carfilzomib and TG02 in multiple myeloma.Triptolide induces apoptosis in human leukemia cells through caspase-3-mediated ROCK1 activation and MLC phosphorylation.Alpha fetoprotein antagonises benzyl isothiocyanate inhibition of the malignant behaviors of hepatocellular carcinoma cells.Miltirone exhibits antileukemic activity by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction pathways.In vitro and in vivo antitumour activities of puerarin 6″-O-xyloside on human lung carcinoma A549 cell line via the induction of the mitochondria-mediated apoptosis pathway.Anti-tumor effects of atractylenolide I isolated from Atractylodes macrocephala in human lung carcinoma cell lines.Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry.Benzyl isothiocyanate induces reactive oxygen species-initiated autophagy and apoptosis in human prostate cancer cells.Polyphyllin D induces apoptosis in K562/A02 cells through G2/M phase arrest.Discovering proteasomal deubiquitinating enzyme inhibitors for cancer therapy: lessons from rational design, nature and old drug reposition
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P2860
Downregulation of Mcl-1 through inhibition of translation contributes to benzyl isothiocyanate-induced cell cycle arrest and apoptosis in human leukemia cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 February 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Downregulation of Mcl-1 throug ...... tosis in human leukemia cells.
@en
Downregulation of Mcl-1 throug ...... tosis in human leukemia cells.
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type
label
Downregulation of Mcl-1 throug ...... tosis in human leukemia cells.
@en
Downregulation of Mcl-1 throug ...... tosis in human leukemia cells.
@nl
prefLabel
Downregulation of Mcl-1 throug ...... tosis in human leukemia cells.
@en
Downregulation of Mcl-1 throug ...... tosis in human leukemia cells.
@nl
P2093
P2860
P356
P1476
Downregulation of Mcl-1 throug ...... tosis in human leukemia cells.
@en
P2093
P2860
P356
10.1038/CDDIS.2013.41
P577
2013-02-28T00:00:00Z