Critical roles of the PI3K/Akt signaling pathway in T cell development
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Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphateSignaling by the phosphoinositide 3-kinase family in immune cellsComparative transcriptome analyses of seven anurans reveal functions and adaptations of amphibian skinA kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice.Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation.Unraveling natalizumab effects on deregulated miR-17 expression in CD4+ T cells of patients with relapsing-remitting multiple sclerosis.An overview of IL-7 biology and its use in immunotherapy.T-cell and B-cell signaling biomarkers and treatment targets in lupus.Vorinostat interferes with the signaling transduction pathway of T-cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T-cell lymphoma.An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.Group I metabotropic glutamate receptor mediated dynamic immune dysfunction in children with fragile X syndrome.Accelerated thymocyte maturation in IL-12Rβ2-deficient mice contributes to increased susceptibility to autoimmune inflammatory demyelinationZebrafish screen identifies novel compound with selective toxicity against leukemia.Lipid signaling in T-cell development and functionSuppression of leukemia development caused by PTEN loss.Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell ProtectionSelected extracellular microRNA as potential biomarkers of multiple sclerosis activity--preliminary study.T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10.Phosphoinositide and inositol phosphate analysis in lymphocyte activationSignal integration by Akt regulates CD8 T cell effector and memory differentiation.Update on the Pathophysiological Role of Intracellular Signaling Pathways in Atherosclerotic Plaques and Ischemic MyocardiumInterleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation.Altered AKT1 and MAPK1 gene expression on peripheral blood mononuclear cells and correlation with T-helper-transcription factors in systemic lupus erythematosus patientsNon-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's diseasePrior TLR5 induction in human T cells results in a transient potentiation of subsequent TCR-induced cytokine production.Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations.Metabolism, migration and memory in cytotoxic T cells.TCR signaling requirements for activating T cells and for generating memory.MicroRNAs as active players in the pathogenesis of multiple sclerosis.Synergistic effects of interleukin-7 and pre-T cell receptor signaling in human T cell development.The functions of tumor suppressor PTEN in innate and adaptive immunity.A practical guide to build de-novo assemblies for single tissues of non-model organisms: the example of a Neotropical frog.Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.The role of the PI3K-AKT kinase pathway in T-cell development beyond the beta checkpoint.In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis.From the loading dock to the boardroom: a new job for Akt kinase.Distinct oncogenic Ras signals characterized by profound differences in flux through the RasGDP/RasGTP cycle
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Critical roles of the PI3K/Akt signaling pathway in T cell development
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Critical roles of the PI3K/Akt signaling pathway in T cell development
@en
Critical roles of the PI3K/Akt signaling pathway in T cell development.
@nl
type
label
Critical roles of the PI3K/Akt signaling pathway in T cell development
@en
Critical roles of the PI3K/Akt signaling pathway in T cell development.
@nl
prefLabel
Critical roles of the PI3K/Akt signaling pathway in T cell development
@en
Critical roles of the PI3K/Akt signaling pathway in T cell development.
@nl
P2860
P1433
P1476
Critical roles of the PI3K/Akt signaling pathway in T cell development
@en
P2093
Gary A Koretzky
Marisa M Juntilla
P2860
P304
P356
10.1016/J.IMLET.2007.12.008
P577
2008-01-10T00:00:00Z