HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches.
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Oncogenes and RNA splicing of human tumor virusesDisruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancerGenome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30.Genes related to antiviral activity, cell migration, and lysis are differentially expressed in CD4(+) T cells in human t cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis patients.HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes.Common threads in persistent viral infectionsImmune activation induces immortalization of HTLV-1 LTR-Tax transgenic CD4+ T cellsLocalization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery.Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor virusesHBZ stimulates brain-derived neurotrophic factor/TrkB autocrine/paracrine signaling to promote survival of human T-cell leukemia virus type 1-Infected T cellsRole of post-translational modifications of HTLV-1 Tax in NF-κB activation.C7a, a biphosphinic cyclopalladated compound, efficiently controls the development of a patient-derived xenograft model of adult T cell leukemia/lymphoma.Inhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells.Ras signaling contributes to survival of human T-cell leukemia/lymphoma virus type 1 (HTLV-1) Tax-positive T-cells.The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cellsLow nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activationHTLV-1 Yin and Yang: Rex and p30 master regulators of viral mRNA trafficking.NF-κB as a target for oncogenic viruses.Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signalingHTLV gene regulation: because size matters, transcription is not enough.Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis.Cell surface markers in HTLV-1 pathogenesis.HTLV-1 Rex: the courier of viral messages making use of the host vehicle.Induction of cell cycle arrest, DNA damage, and apoptosis by nimbolide in human renal cell carcinoma cells.Delta-tocotrienol induces apoptotic cell death via depletion of intracellular squalene in ED40515 cells.Evaluation of T Regulatory Lymphocytes Transcription Factors in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Patients.The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein.Genistein induces apoptotic cell death associated with inhibition of the NF-κB pathway in adult T-cell leukemia cells.Upregulation of hsa-miR-125b in HTLV-1 asymptomatic carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis patients.Clinical features of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in northeast Iran.A novel medium-throughput biological assay system for HTLV-1 infectivity and drug discovery.Transcription Factor and lncRNA Regulatory Networks Identify Key Elements in Lung Adenocarcinoma.
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HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2008
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
HTLV-1 and apoptosis: role in ...... ces in therapeutic approaches.
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HTLV-1 and apoptosis: role in ...... ces in therapeutic approaches.
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type
label
HTLV-1 and apoptosis: role in ...... ces in therapeutic approaches.
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HTLV-1 and apoptosis: role in ...... ces in therapeutic approaches.
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HTLV-1 and apoptosis: role in ...... ces in therapeutic approaches.
@en
HTLV-1 and apoptosis: role in ...... ces in therapeutic approaches.
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P2860
P1433
P1476
HTLV-1 and apoptosis: role in ...... ces in therapeutic approaches.
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P2093
Christophe Nicot
John M Taylor
P2860
P2888
P304
P356
10.1007/S10495-008-0208-7
P577
2008-06-01T00:00:00Z