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Versatile biocatalysis of fungal cytochrome P450 monooxygenasesOptimization of the bacterial cytochrome P450 BM3 system for the production of human drug metabolitesOxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic AcidsStructural Evidence for Enhancement of Sequential Vitamin D3 Hydroxylation Activities by Directed Evolution of Cytochrome P450 Vitamin D3 HydroxylaseA single mutation at the ferredoxin binding site of P450 Vdh enables efficient biocatalytic production of 25-hydroxyvitamin D(3)The Oxygen Dilemma: A Severe Challenge for the Application of Monooxygenases?Use of chemical auxiliaries to control p450 enzymes for predictable oxidations at unactivated C-h bonds of substratesEngineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediationResin acid conversion with CYP105A1: an enzyme with potential for the production of pharmaceutically relevant diterpenoids.Enzymatic functionalization of carbon-hydrogen bonds.Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation in Rhodococcus jostii RHA1.Cytochrome P450: taming a wild type enzymeSteroid conversion with CYP106A2 - production of pharmaceutically interesting DHEA metabolites.Simultaneous measurement of CYP1A2 activity, regioselectivity, and coupling: Implications for environmental sensitivity of enzyme-substrate binding.A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale.The influence of microbial physiology on biocatalyst activity and efficiency in the terminal hydroxylation of n-octane using Escherichia coli expressing the alkane hydroxylase, CYP153A6.Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins.Controlling substrate specificity and product regio- and stereo-selectivities of P450 enzymes without mutagenesis.Production of human phase 1 and 2 metabolites by whole-cell biotransformation with recombinant microbes.P450(BM3) (CYP102A1): connecting the dots.Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations.Bacterial whole-cell biocatalysts by surface display of enzymes: toward industrial application.Catalytic oxygen activation versus autoxidation for industrial applications: a physicochemical approach.Guidelines for development and implementation of biocatalytic P450 processes.CYP267A1 and CYP267B1 from Sorangium cellulosum So ce56 are Highly Versatile Drug Metabolizers.Type II ligands as chemical auxiliaries to favor enzymatic transformations by P450 2E1.Effect of cell permeability and dehydrogenase expression on octane activation by CYP153A6-based whole cell Escherichia coli catalysts.Fusion to Hydrophobin HFBI Improves the Catalytic Performance of a Cytochrome P450 System.Biosynthetic pathway for the cyanide-free production of phenylacetonitrile in Escherichia coli by utilizing plant cytochrome P450 79A2 and bacterial aldoxime dehydratase.Selective oxidative demethylation of veratric acid to vanillic acid by CYP199A4 from Rhodopseudomonas palustris HaA2.Engineering of a hybrid biotransformation system for cytochrome P450sca-2 in Escherichia coli.Screening for cytochrome P450 expression in Pichia pastoris whole cells by P450-carbon monoxide complex determination.Semi-rational engineering of cytochrome P450sca-2 in a hybrid system for enhanced catalytic activity: insights into the important role of electron transfer.Simultaneous detection of NADPH consumption and H2O2 production using the Ampliflu™ Red assay for screening of P450 activities and uncoupling.Mutagenesis and expression of methane monooxygenase to alter regioselectivity with aromatic substrates.Peroxide-dependent oxidation reactions catalyzed by CYP191A1 from Mycobacterium smegmatis.Exploring PTDH-P450BM3 Variants for the Synthesis of Drug Metabolites.Design and characterization of an efficient CYP105A1-based whole-cell biocatalyst for the conversion of resin acid diterpenoids in permeabilized Escherichia coli.Whole-cell-based CYP153A6-catalyzed (S)-limonene hydroxylation efficiency depends on host background and profits from monoterpene uptake via AlkL.Metabolism of Oral Turinabol by Human Steroid Hormone-Synthesizing Cytochrome P450 Enzymes.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 04 March 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Heme-iron oxygenases: powerful industrial biocatalysts?
@en
Heme-iron oxygenases: powerful industrial biocatalysts?
@nl
type
label
Heme-iron oxygenases: powerful industrial biocatalysts?
@en
Heme-iron oxygenases: powerful industrial biocatalysts?
@nl
prefLabel
Heme-iron oxygenases: powerful industrial biocatalysts?
@en
Heme-iron oxygenases: powerful industrial biocatalysts?
@nl
P1476
Heme-iron oxygenases: powerful industrial biocatalysts?
@en
P2093
Mattijs K Julsing
Sjef Cornelissen
P304
P356
10.1016/J.CBPA.2008.01.029
P577
2008-03-04T00:00:00Z