Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance.
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Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cellsRegulating telomere length from the inside out: the replication fork modelNucleases in homologous recombination as targets for cancer therapyRequirement for flap endonuclease 1 (FEN1) to maintain genomic stability and transcriptional gene silencing in Arabidopsis.The human Suv3 helicase interacts with replication protein A and flap endonuclease 1 in the nucleusThe FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.Functional regulation of FEN1 nuclease and its link to cancerFen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancerYY1 suppresses FEN1 over-expression and drug resistance in breast cancerRECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.Flap endonuclease 1.Telomere replication: poised but puzzlingA novel method for monitoring functional lesion-specific recruitment of repair proteins in live cells.Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in.Mapping the FEN1 interaction domain with hTERT.CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity.The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells.DNA-Directed Polymerase Subunits Play a Vital Role in Human Telomeric Overhang Processing.
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Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Human flap endonuclease I is i ...... mediated telomere maintenance.
@en
Human flap endonuclease I is i ...... mediated telomere maintenance.
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type
label
Human flap endonuclease I is i ...... mediated telomere maintenance.
@en
Human flap endonuclease I is i ...... mediated telomere maintenance.
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prefLabel
Human flap endonuclease I is i ...... mediated telomere maintenance.
@en
Human flap endonuclease I is i ...... mediated telomere maintenance.
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P2093
P2860
P356
P1476
Human flap endonuclease I is i ...... mediated telomere maintenance.
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P2093
Amruta Bhusari
Binghui Shen
Shilpa Sampathi
Weihang Chai
P2860
P304
P356
10.1074/JBC.M805362200
P407
P577
2008-12-09T00:00:00Z