A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
about
High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming eventGlobal Cell Proteome Profiling, Phospho-signaling and Quantitative Proteomics for Identification of New Biomarkers in Acute Myeloid Leukemia PatientsCombination of BCL11A siRNA with vincristine increases the apoptosis of SUDHL6 cells.p53-Dependent transcriptional responses to interleukin-3 signalingBCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.Bcl11a is essential for lymphoid development and negatively regulates p53.Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification.Downregulation of BCL11A by siRNA induces apoptosis in B lymphoma cell lines.Vesicular Stomatitis Virus G Glycoprotein and ATRA Enhanced Bystander Killing of Chemoresistant Leukemic Cells by Herpes Simplex Virus Thymidine Kinase/Ganciclovir.Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation.Inhibitors of LSD1 as a potential therapy for acute myeloid leukemia.Regulation of p21 by TWIST2 contributes to its tumor-suppressor function in human acute myeloid leukemia.Gene expression profile analysis of SUDHL6 cells with siRNA-mediated BCL11A downregulation.Bcl11a Deficiency Leads to Hematopoietic Stem Cell Defects with an Aging-like Phenotype.Aberrant expression of ecotropic viral integration site-1 in acute myeloid leukemia and acute lymphoblastic leukemia.Global phosphoproteome analysis of human bone marrow reveals predictive phosphorylation markers for the treatment of acute myeloid leukemia with quizartinibThe gene expression patterns of BMPR2, EP300, TGFβ2, and TNFAIP3 in B-Lymphoma cells.The expression pattern of Bcl11a, Mdm2 and Pten genes in B-cell acute lymphoblastic leukemia.The mutational spectrum of the NF1 gene in neurofibromatosis type I patients from UAE.
P2860
Q28299462-6CDF2724-A345-441D-B806-3544BA3E751AQ33555287-51C351DA-27A1-40AE-93EA-FECE332FC2F0Q33864314-A4B95CDC-720C-4C3A-B80D-CFF4BD7F32E9Q34163536-E573A036-4D4F-4481-8979-A6759D58DAB2Q35114304-744E0CD5-941C-4CC8-83DF-7E012534BBA9Q36478284-FA557057-D933-477F-A60D-C53B6DFD6A94Q36515569-75D65F95-3562-44B6-93AC-301EC5B1B1E3Q36964364-9A5BEB5D-0FC0-438B-B471-FB7F8FB43800Q37641982-BB77CED4-0D63-4442-93A3-87009AA87238Q37684212-75A1B4FB-F80B-429D-84E8-54BB950A0C5DQ37845436-5B484513-05C3-48E8-98D8-C2E1A6F5BA30Q38808175-1913CF12-5CAD-4C0E-AA92-B387DD5DE90AQ38969143-FB609BE9-F241-46FE-88C3-BA4935C58494Q38973429-295EDFBC-55F3-4BCF-AB53-4406FCC4462BQ41363689-D6CCFF77-3E32-4B91-849D-75721F7B4CF6Q42218756-DFF6D27E-FB96-4FC3-B711-646A36496C8BQ42415850-16BDB864-5110-4A27-B900-186D85F7F4EFQ42944687-5F61350E-6F96-4143-8E8C-0220F7EABFA7Q50201177-9133DF9B-1386-4846-807E-92870511E894Q54228124-F3258248-BD44-4238-AEC5-8CB0D483B1F0
P2860
A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A retroviral mutagenesis scree ...... the Nf1 tumor suppressor gene.
@en
A retroviral mutagenesis scree ...... the Nf1 tumor suppressor gene.
@nl
type
label
A retroviral mutagenesis scree ...... the Nf1 tumor suppressor gene.
@en
A retroviral mutagenesis scree ...... the Nf1 tumor suppressor gene.
@nl
prefLabel
A retroviral mutagenesis scree ...... the Nf1 tumor suppressor gene.
@en
A retroviral mutagenesis scree ...... the Nf1 tumor suppressor gene.
@nl
P2093
P2860
P1433
P1476
A retroviral mutagenesis scree ...... the Nf1 tumor suppressor gene.
@en
P2093
David A Largaespada
Kevin M Shannon
Margaret R Wallace
Mignon L Loh
Peter J Valk
Ruud Delwel
P2860
P304
P356
10.1182/BLOOD-2008-03-144436
P407
P577
2008-10-23T00:00:00Z