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Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastomaHedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma modelInhibition of ERβ induces resistance to cisplatin by enhancing Rad51-mediated DNA repair in human medulloblastoma cell linesFenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell SpheroidsNew pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells.Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cellsmiR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastomaHigh levels of PROM1 (CD133) transcript are a potential predictor of poor prognosis in medulloblastomaCross-talk between T-Ag presence and pRb family and p53/p73 signaling in mouse and human medulloblastoma.Isolation, enrichment, and maintenance of medulloblastoma stem cellsMiR-148a, a microRNA upregulated in the WNT subgroup tumors, inhibits invasion and tumorigenic potential of medulloblastoma cells by targeting Neuropilin 1.Adenomatous polyposis coli is essential for both neuronal differentiation and maintenance of adult neural stem cells in subventricular zone and hippocampus.The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases in vitro drug delivery across blood-brain barrier cells.In vitro Natural Killer Cell Immunotherapy for Medulloblastoma.Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome.Real-time PCR assay based on the differential expression of microRNAs and protein-coding genes for molecular classification of formalin-fixed paraffin embedded medulloblastomas.Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups.Genetically engineered mouse models of brain cancer and the promise of preclinical testingAnalysis of microsatellite instability in medulloblastoma.Genetics of medulloblastoma: clues for novel therapies.MicroRNAs in brain tumors : a new diagnostic and therapeutic perspective?The role of radiotherapy in adult medulloblastoma: long-term single-institution experience and a review of the literature.Review: personalized mice: modelling the molecular heterogeneity of medulloblastoma.Matching mice to malignancy: molecular subgroups and models of medulloblastoma.Nuclear IRS-1 and cancerFrom small to big: microRNAs as new players in medulloblastomas.The role of microRNAs in medulloblastoma.Targeted treatment for sonic hedgehog-dependent medulloblastoma.Antitumour activity of AMG 900 alone or in combination with histone deacetylase inhibitor SaHa on medulloblastoma cell lines.Immunohistochemical expression of sulfhydryl oxidase (QSOX1) in pediatric medulloblastomas.Effect of small nuclear ribonucleoprotein-associated polypeptide N on the proliferation of medulloblastoma cells.A novel small molecular STAT3 inhibitor, LY5, inhibits cell viability, cell migration, and angiogenesis in medulloblastoma cells.MiR-383 is downregulated in medulloblastoma and targets peroxiredoxin 3 (PRDX3).Expression patterns and potential roles of SIRT1 in human medulloblastoma cells in vivo and in vitro.RalA is overactivated in medulloblastoma.Prognostic value of the TP53 Arg72Pro single-nucleotide polymorphism and susceptibility to medulloblastoma in a cohort of Brazilian patients.Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma.Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways.The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cellsSurvivin expression in medulloblastoma: a possible marker for survival.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Medulloblastoma: from molecular pathology to therapy
@en
Medulloblastoma: from molecular pathology to therapy.
@nl
type
label
Medulloblastoma: from molecular pathology to therapy
@en
Medulloblastoma: from molecular pathology to therapy.
@nl
prefLabel
Medulloblastoma: from molecular pathology to therapy
@en
Medulloblastoma: from molecular pathology to therapy.
@nl
P2093
P2860
P1476
Medulloblastoma: from molecular pathology to therapy
@en
P2093
Alessandra Rossi
Giuseppe Russo
Krzysztof Reiss
Valentina Caracciolo
P2860
P304
P356
10.1158/1078-0432.CCR-07-2072
P407
P577
2008-02-01T00:00:00Z