Nucleotide deficiency promotes genomic instability in early stages of cancer development
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FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stressCyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repairUnbalanced replication as a major source of genetic instability in cancer cellsTargeting DNA Replication Stress for Cancer TherapyOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingRetinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategiesRibosomopathies: how a common root can cause a tree of pathologiesRegulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implicationsNetwork calisthenics: control of E2F dynamics in cell cycle entryTwists in views on RB functions in cellular signaling, metabolism and stem cellsSerine, glycine and one-carbon units: cancer metabolism in full circleAtaxia-telangiectasia: future prospectsRB1: a prototype tumor suppressor and an enigmaThe multiple connections between pRB and cell metabolismMolecular mechanisms underlying RB protein functionGenetically-defined metabolic reprogramming in cancerAutophagy-mediated tumor promotionTumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage ResponseThe Role of the DNA Damage Response throughout the Papillomavirus Life CycleReplication stress in Mammalian cells and its consequences for mitosisPolymerase δ replicates both strands after homologous recombination-dependent fork restartInitiation of genome instability and preneoplastic processes through loss of Fhit expressionSIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolismLoss of RBF1 changes glutamine catabolismDNA replication stress mediates APOBEC3 family mutagenesis in breast cancerSpontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells.Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state.N-Aroyl indole thiobarbituric acids as inhibitors of DNA repair and replication stress response polymerases.Papillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrationsRibonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA ReplicationArabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control.Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.MYC and the control of DNA replication.Break-induced replication repair of damaged forks induces genomic duplications in human cells.Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.Induction of homologous recombination following in utero exposure to DNA-damaging agents.PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.Expression of the HPV18/E6 oncoprotein induces DNA damage.The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia.
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Nucleotide deficiency promotes genomic instability in early stages of cancer development
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Nucleotide deficiency promotes genomic instability in early stages of cancer development
@en
Nucleotide deficiency promotes genomic instability in early stages of cancer development.
@nl
type
label
Nucleotide deficiency promotes genomic instability in early stages of cancer development
@en
Nucleotide deficiency promotes genomic instability in early stages of cancer development.
@nl
prefLabel
Nucleotide deficiency promotes genomic instability in early stages of cancer development
@en
Nucleotide deficiency promotes genomic instability in early stages of cancer development.
@nl
P2093
P2860
P1433
P1476
Nucleotide deficiency promotes genomic instability in early stages of cancer development
@en
P2093
Aaron Bensimon
Assaf C Bester
Batsheva Kerem
Donna S Shewach
Gideon Zamir
Maayan Roniger
Malka Chaoat
Michael M Im
Yifat S Oren
P2860
P304
P356
10.1016/J.CELL.2011.03.044
P407
P577
2011-04-01T00:00:00Z