Zinc transporter (ZnT)8(186-194) is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients.
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Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitusT cell epitopes and post-translationally modified epitopes in type 1 diabetesCurrent and Future Clinical Applications of Zinc Transporter-8 in Type 1 Diabetes MellitusNavigating diabetes-related immune epitope data: resources and tools provided by the Immune Epitope Database (IEDB)Detection of serum antibodies cross-reacting with Mycobacterium avium subspecies paratuberculosis and beta-cell antigen zinc transporter 8 homologous peptides in patients with high-risk proliferative diabetic retinopathyZnT8-reactive T cells are weakly pathogenic in NOD mice but can participate in diabetes under inflammatory conditionsZinc transporter 8 and MAP3865c homologous epitopes are recognized at T1D onset in Sardinian children.The prevalence and predictive value of the SLC30A8 R325W polymorphism and zinc transporter 8 autoantibodies in the development of GDM and postpartum type 1 diabetes.β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure.Changes in Zinc Transporter 8 Autoantibodies Following Type 1 Diabetes Onset: The Type 1 Diabetes Genetics Consortium Autoantibody Workshop.HLA-B7-restricted islet epitopes are differentially recognized in type 1 diabetic children and adults and form weak peptide-HLA complexes.Novel autoantigens in type 1 diabetes.Narrowing in on the anti-β cell-specific T cells: looking 'where the action is'.Zinc homeostasis in the metabolic syndrome and diabetes.Mycobacterium avium ss. paratuberculosis Zoonosis - The Hundred Year War - Beyond Crohn's Disease.Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice.A distinct immunogenic region of glutamic acid decarboxylase 65 is naturally processed and presented by human islet cells to cytotoxic CD8 T cells.Expression analysis of zinc transporters in resting and stimulated human peripheral blood mononuclear cells.Autoreactive T cells in type 1 diabetes.A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.
P2860
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P2860
Zinc transporter (ZnT)8(186-194) is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 April 2012
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Zinc transporter (ZnT)8(186-19 ...... -A2+ type 1 diabetic patients.
@en
Zinc transporter
@nl
type
label
Zinc transporter (ZnT)8(186-19 ...... -A2+ type 1 diabetic patients.
@en
Zinc transporter
@nl
prefLabel
Zinc transporter (ZnT)8(186-19 ...... -A2+ type 1 diabetic patients.
@en
Zinc transporter
@nl
P2093
P2860
P50
P1433
P1476
Zinc transporter (ZnT)8(186-19 ...... A-A2+ type 1 diabetic patients
@en
P2093
D Dubois-Laforgue
F A Lemonnier
H W Davidson
J C Hutton
P2860
P2888
P304
P356
10.1007/S00125-012-2543-Z
P577
2012-04-20T00:00:00Z