HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis
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Interferon-gamma production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1(*)0401 and HLA-DQ8The challenge of early synovitis: multiple pathways to a common clinical syndromeThe genetics of rheumatoid arthritis and the need for animal models to find and understand the underlying genesAssociation of MHC and rheumatoid arthritis. Regulatory role of HLA class II molecules in animal models of RA: studies on transgenic/knockout miceAssociation of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and menIdentification of antigenic epitopes on human allergens: studies with HLA transgenic miceDifferential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigeInduction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.Identification of HLA class II-restricted determinants of Mycobacterium tuberculosis-derived proteins by using HLA-transgenic, class II-deficient mice.HLA class II transgenic mice as models of human diseases.Transgenic mouse models of rheumatoid arthritis.Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice.Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin BHLA class II transgenic mice: models of the human CD4+ T-cell immune response.Short ragweed allergen induces eosinophilic lung disease in HLA-DQ transgenic mice.Relationship between Poor Immunogenicity of HLA-A2-Restricted Peptide Epitopes and Paucity of Naïve CD8(+) T-Cell Precursors in HLA-A2-Transgenic Mice.New revelations in susceptibility to autoimmune thyroiditis by the use of H2 and HLA class II transgenic models.A humanized model of experimental autoimmune uveitis in HLA class II transgenic miceTrans heterodimer between two non-arthritis-associated HLA alleles can predispose to arthritis in humanized miceUveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cellsTo B or not to B: role of B cells in pathogenesis of arthritis in HLA transgenic mice.Mice expressing HLA-DQ6alpha8beta transgenes develop polychondritis spontaneously.A review of the MHC genetics of rheumatoid arthritis.Deletion of fcgamma receptor IIB renders H-2(b) mice susceptible to collagen-induced arthritisType 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.High-throughput, high-fidelity HLA genotyping with deep sequencing.HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA-DRB1*0301 (DR3) geneAn HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen.Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice.Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones.Spontaneous autoimmune myocarditis and cardiomyopathy in HLA-DQ8.NODAbo transgenic mice.Vaccine based on a ubiquitous cysteinyl protease and streptococcal pyrogenic exotoxin A protects against Streptococcus pyogenes sepsis and toxic shock.B cells as effectors and regulators of sex-biased arthritis.Zinc transporter (ZnT)8(186-194) is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients.Autoimmune cardiomyopathy and heart block develop spontaneously in HLA-DQ8 transgenic IAbeta knockout NOD miceThe role of collagen antibodies in mediating arthritis.Identification of CD4 T-cell epitopes in soluble liver antigen/liver pancreas autoantigen in autoimmune hepatitisHLA-DQB1 polymorphism determines incidence, onset, and severity of collagen-induced arthritis in transgenic mice. Implications in human rheumatoid arthritisInduction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice.Latest animal models for anti-HIV drug discovery.
P2860
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P2860
HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
HLA-DQ8 transgenic mice are hi ...... model for human polyarthritis
@ast
HLA-DQ8 transgenic mice are hi ...... model for human polyarthritis
@en
type
label
HLA-DQ8 transgenic mice are hi ...... model for human polyarthritis
@ast
HLA-DQ8 transgenic mice are hi ...... model for human polyarthritis
@en
prefLabel
HLA-DQ8 transgenic mice are hi ...... model for human polyarthritis
@ast
HLA-DQ8 transgenic mice are hi ...... model for human polyarthritis
@en
P2093
P2860
P356
P1476
HLA-DQ8 transgenic mice are hi ...... model for human polyarthritis
@en
P2093
D Cosgrove
G H Nabozny
H S Luthra
J M Baisch
M M Griffiths
P2860
P356
10.1084/JEM.183.1.27
P407
P577
1996-01-01T00:00:00Z