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Animal models of hemophilia and related bleeding disorders.

Animal models of hemophilia and related bleeding disorders.

http://www.wikidata.org/entity/Q37091290

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Current animal models of hemophilia: the state of the art Companion animals: Translational scientist's new best friends A new mouse model for wound healing in hemophilia A.Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test - Demonstrated in vitro and ex vivo.Severe Hemophilia A in a Male Old English Sheep Dog with a C→T Transition that Created a Premature Stop Codon in Factor VIII.Animal medical genetics: a perspective on the epidemiology and control of inherited disorders.Canine models of inherited bleeding disorders in the development of coagulation assays, novel protein replacement and gene therapies.Anti-factor IXa/X bispecific antibody ACE910 prevents joint bleeds in a long-term primate model of acquired hemophilia A.A novel F8 -/- rat as a translational model of human hemophilia A.Factor XI-deficient mice exhibit increased bleeding after injury to the saphenous vein.Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A.Decellularized human placenta supports hepatic tissue and allows rescue in acute liver failure.

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Animal models of hemophilia and related bleeding disorders.

http://www.wikidata.org/entity/Q37091290

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Animal models of hemophilia and related bleeding disorders.

@en

Animal models of hemophilia and related bleeding disorders.

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type

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Animal models of hemophilia and related bleeding disorders.

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Animal models of hemophilia and related bleeding disorders.

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prefLabel

Animal models of hemophilia and related bleeding disorders.

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Animal models of hemophilia and related bleeding disorders.

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J.SEMINHEMATOL.2013.03.023

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Seminars in Hematology

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Animal models of hemophilia and related bleeding disorders.

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Jay N Lozier

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Timothy C Nichols

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P2860

Shear-dependent changes in the three-dimensional structure of human von Willebrand factor

Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor

Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A

Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase

Creation of a mouse expressing defective human factor IX

A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion.

Aberrant splicing and premature termination of transcription of the FVIII gene as a cause of severe canine hemophilia A: similarities with the intron 22 inversion mutation in human hemophilia.

Sequence of the human factor VIII-associated gene is conserved in mouse.

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175-184

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scholarly article

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10.1053/J.SEMINHEMATOL.2013.03.023

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2

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2013-04-01T00:00:00Z

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