Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination - Wikidata - wikimedia - TriplyDB

Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination

Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination

http://www.wikidata.org/entity/Q37091343

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Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex Transdifferentiation. Sequential histone-modifying activities determine the robustness of transdifferentiation Histone demethylases in chromatin biology and beyond Chromatin dynamics during cellular reprogramming Reprogramming of cell fate: epigenetic memory and the erasure of memories past The Maternal Effect Genes UTX and JMJD3 Play Contrasting Roles in Mus musculus Preimplantation Embryo Development.JMJD3 as an epigenetic regulator in development and disease Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity.MOF-associated complexes ensure stem cell identity and Xist repression.The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated MIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells.Jmjd3-mediated epigenetic regulation of inflammatory cytokine gene expression in serum amyloid A-stimulated macrophages.Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.The molecular balancing act of p16(INK4a) in cancer and aging.Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.The dosage of Patz1 modulates reprogramming process.Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation.The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner.TRIM26 negatively regulates interferon-β production and antiviral response through polyubiquitination and degradation of nuclear IRF3 Chemical approaches to cell reprogramming Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.Targeting epigenetic regulations in cancer Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription.JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells.Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth.The roles of Jumonji-type oxygenases in human disease.An epigenetic view of B-cell disorders.Transcription factor-mediated reprogramming: epigenetics and therapeutic potential.Inhibitors of Protein Methyltransferases and Demethylases.Regulatory factors of induced pluripotency: current status.Epigenetic Control of Reprogramming and Transdifferentiation by Histone Modifications.JMJD8 is a positive regulator of TNF-induced NF-κB signaling.USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.Ubiquitylation-dependent regulation of NEIL1 by Mule and TRIM26 is required for the cellular DNA damage response.

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Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination

http://www.wikidata.org/entity/Q37091343

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on February 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Jmjd3 inhibits reprogramming b ...... eting PHF20 for ubiquitination

@en

Jmjd3 inhibits reprogramming b ...... ting PHF20 for ubiquitination.

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type

label

Jmjd3 inhibits reprogramming b ...... eting PHF20 for ubiquitination

@en

Jmjd3 inhibits reprogramming b ...... ting PHF20 for ubiquitination.

@nl

prefLabel

Jmjd3 inhibits reprogramming b ...... eting PHF20 for ubiquitination

@en

Jmjd3 inhibits reprogramming b ...... ting PHF20 for ubiquitination.

@nl

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J.CELL.2013.02.006

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Jmjd3 inhibits reprogramming b ...... eting PHF20 for ubiquitination

@en

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Helen Y Wang

http://www.w3.org/2001/XMLSchema#string

Qingtian Li

http://www.w3.org/2001/XMLSchema#string

Qingyuan Zhu

http://www.w3.org/2001/XMLSchema#string

Rong-Fu Wang

http://www.w3.org/2001/XMLSchema#string

Stephen Ayers

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Wei Zhao

http://www.w3.org/2001/XMLSchema#string

Yidong Chen

http://www.w3.org/2001/XMLSchema#string

Yifeng Gu

http://www.w3.org/2001/XMLSchema#string

Zhong Shi

http://www.w3.org/2001/XMLSchema#string

P2860

Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex

Tudor, MBT and chromo domains gauge the degree of lysine methylation

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

Direct cell reprogramming is a stochastic process amenable to acceleration

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

Glioma-expressed antigen 2 (GLEA2): a novel protein that can elicit immune responses in glioblastoma patients and some controls

Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins

Induced pluripotent stem cell lines derived from human somatic cells

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1037-1050

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scholarly article

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10.1016/J.CELL.2013.02.006

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5

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152

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2013-02-01T00:00:00Z

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235773953

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23452852

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protein ubiquitination

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