The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective. - Wikidata - wikimedia - TriplyDB

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective.

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective.

http://www.wikidata.org/entity/Q37095615

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Recent developments of protein kinase inhibitors as potential AD therapeutics Targeting innate immunity for neurodegenerative disorders of the central nervous system Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible connection The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases Rodent models of neuroinflammation for Alzheimer's disease The role of inflammasome in Alzheimer's disease Alterations in immune cells and mediators in the brain: it's not always neuroinflammation!Interleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore.[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats Emerging Roles for the Immune System in Traumatic Brain Injury Lessons from Microglia Aging for the Link between Inflammatory Bone Disorders and Alzheimer's Disease Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy Effects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 mice Up-regulation and activation of the P2Y(2) nucleotide receptor mediate neurite extension in IL-1β-treated mouse primary cortical neurons Pharmacogenetic analysis of the effects of polymorphisms in APOE, IDE and IL1B on a ketone body based therapeutic on cognition in mild to moderate Alzheimer's disease; a randomized, double-blind, placebo-controlled study.Glial contributions to neurodegeneration in tauopathies.Role of Medium Chain Triglycerides (Axona®) in the Treatment of Mild to Moderate Alzheimer's Disease.Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer's disease: Alleviation by pantethine.Plexin-A1 is required for Toll-like receptor-mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy Association of IL1A and IL1B loci with primary open angle glaucoma.Combination therapy with an anti-IL-1β antibody and GAD65 DNA vaccine can reverse recent-onset diabetes in the RIP-GP mouse model.1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients Multiplexed Electrochemical Immunosensors for Clinical Biomarkers Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease Metabolic alteration of neuroactive steroids and protective effect of progesterone in Alzheimer's disease-like rats Association of neuropeptide Y (NPY), interleukin-1B (IL1B) genetic variants and correlation of IL1B transcript levels with vitiligo susceptibility Inflammation, but not hypoxia, mediated HIF-1alpha activation depends on COX-2 CNF1 increases brain energy level, counteracts neuroinflammatory markers and rescues cognitive deficits in a murine model of Alzheimer's disease.P2Y receptors in Alzheimer's disease.Induction of an inflammatory loop by interleukin-1β and tumor necrosis factor-α involves NF-kB and STAT-1 in differentiated human neuroprogenitor cells.Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases.SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.Toll-like receptor 2 and NLRP3 cooperate to recognize a functional bacterial amyloid, curli The role of the anaphylatoxins in health and disease.The Nrf2-ARE cytoprotective pathway in astrocytes.Interleukin 1 type 1 receptor restore: a genetic mouse model for studying interleukin 1 receptor-mediated effects in specific cell types Brain interleukin-1β and the intrinsic receptor antagonist control peripheral Toll-like receptor 3-mediated suppression of spontaneous activity in rats.

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The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective.

http://www.wikidata.org/entity/Q37095615

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article científic

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scientific article published on 26 February 2008

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The role of interleukin-1 in n ...... ease: an evolving perspective.

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The role of interleukin-1 in n ...... ease: an evolving perspective.

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The role of interleukin-1 in n ...... ease: an evolving perspective.

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The role of interleukin-1 in n ...... ease: an evolving perspective.

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The role of interleukin-1 in n ...... ease: an evolving perspective.

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Journal of Neuroinflammation

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The role of interleukin-1 in n ...... ease: an evolving perspective.

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M Kerry O'Banion

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Solomon S Shaftel

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W Sue T Griffin

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Creative Commons Attribution 2.0 Generic

P2860

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

CNS immune privilege: hiding in plain sight.

Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice

Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human beta-amyloid.

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Inflammation and Alzheimer's disease

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway

Neutrophils and immunity: challenges and opportunities

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