Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination
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Therapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaquesMapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the Step studyVaccine design for CD8 T lymphocyte responsesHIV-1 vaccine development after STEP.Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys.Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys.Env-expressing autologous T lymphocytes induce neutralizing antibody and afford marked protection against feline immunodeficiency virusIntra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trialsThe influence of delivery vectors on HIV vaccine efficacySimilar T-cell immune responses induced by group M consensus env immunogens with wild-type or minimum consensus variable regions.Novel adenovirus vector-based vaccines for HIV-1.Challenges in the design of a T cell vaccine in the context of HIV-1 diversity.Designing and testing broadly-protective filoviral vaccines optimized for cytotoxic T-lymphocyte epitope coverageUsing multivalent adenoviral vectors for HIV vaccinationRare serotype adenoviral vectors for HIV vaccine development.For protection from HIV-1 infection, more might not be better: a systematic analysis of HIV Gag epitopes of two alleles associated with different outcomes of HIV-1 infection.Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials.Enhanced Recognition of HIV-1 Cryptic Epitopes Restricted by HLA Class I Alleles Associated With a Favorable Clinical Outcome.HIV-1 Subtype C Mosaic Gag Expressed by BCG and MVA Elicits Persistent Effector T Cell Responses in a Prime-Boost Regimen in MiceDistinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages.Hepatitis C genotype 1 mosaic vaccines are immunogenic in mice and induce stronger T-cell responses than natural strains.An HIV-1 Mini Vaccine Induced Long-lived Cellular and Humoral Immune Responses.Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens.Increased Valency of Conserved-mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition.Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces.Towards in silico design of epitope-based vaccines.DNA Immunization for HIV Vaccine Development.Neutralizing antibodies against adenovirus type 2 in normal and HIV-1-infected subjects: Implications for use of Ad2 vectors in vaccines.New developments in an old strategy: heterologous vector primes and envelope protein boosts in HIV vaccine design.Detailed characterization of antibody responses against HIV-1 group M consensus gp120 in rabbits.HIV-infection resistance in PMBC-derived dendritic cells modified with recombinant virus.Conserved HIV Epitopes for an Effective HIV Vaccine.
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Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Expanded breadth of the T-cell ...... ype 1 envelope DNA vaccination
@en
Expanded breadth of the T-cell ...... pe 1 envelope DNA vaccination.
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type
label
Expanded breadth of the T-cell ...... ype 1 envelope DNA vaccination
@en
Expanded breadth of the T-cell ...... pe 1 envelope DNA vaccination.
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prefLabel
Expanded breadth of the T-cell ...... ype 1 envelope DNA vaccination
@en
Expanded breadth of the T-cell ...... pe 1 envelope DNA vaccination.
@nl
P2093
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Expanded breadth of the T-cell ...... ype 1 envelope DNA vaccination
@en
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Norman L Letvin
Sung-Youl Ko
Wing-Pui Kong
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P304
P356
10.1128/JVI.02256-08
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P577
2008-12-24T00:00:00Z