Use of massively parallel ultradeep pyrosequencing to characterize the genetic diversity of hepatitis B virus in drug-resistant and drug-naive patients and to detect minor variants in reverse transcriptase and hepatitis B S antigen.

Use of massively parallel ultradeep pyrosequencing to characterize the genetic diversity of hepatitis B virus in drug-resistant and drug-naive patients and to detect minor variants in reverse transcriptase and hepatitis B S antigen.

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http://www.wikidata.org/entity/Q37099761

Q37099761

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Viral quasispecies evolution Rhinovirus genome evolution during experimental human infection.Dynamics of hepatitis B virus quasispecies in association with nucleos(t)ide analogue treatment determined by ultra-deep sequencing Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome Base-calling algorithm with vocabulary (BCV) method for analyzing population sequencing chromatograms Association of preexisting drug-resistance mutations and treatment failure in hepatitis B patients Establishment of real time allele specific locked nucleic acid quantitative PCR for detection of HBV YIDD (ATT) mutation and evaluation of its application Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data Development of a low bias method for characterizing viral populations using next generation sequencing technology Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection.Beyond the consensus: dissecting within-host viral population diversity of foot-and-mouth disease virus by using next-generation genome sequencing.A Polyglot Approach to Bioinformatics Data Integration: A Phylogenetic Analysis of HIV-1 Hospital cluster of HBV infection: molecular evidence of patient-to-patient transmission through lancing device.Ultra-deep sequencing reveals high prevalence and broad structural diversity of hepatitis B surface antigen mutations in a global population Error correction of next-generation sequencing data and reliable estimation of HIV quasispecies.Coexistence of HBsAg and HBsAb in a difficult-to-treat chronic hepatitis B: loss of HBsAg with entecavir plus tenofovir combination Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing.Comparison of quasispecies diversity of HCV between chronic hepatitis c and hepatocellular carcinoma by Ultradeep pyrosequencing.Evaluation of intra-host variants of the entire hepatitis B virus genome Detection of hepatitis B virus genotypic resistance mutations by coamplification at lower denaturation temperature-PCR coupled with sanger sequencing.Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy.Detection of mixed populations of wild-type and YMDD hepatitis B variants by pyrosequencing in acutely and chronically infected patients.A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads.Read length versus depth of coverage for viral quasispecies reconstruction Clinical application of estimating hepatitis B virus quasispecies complexity by massive sequencing: correlation between natural evolution and on-treatment evolution.BAsE-Seq: a method for obtaining long viral haplotypes from short sequence reads.Overestimation of incidence of hepatitis B virus mixed-genotype infections by use of the new line probe INNO-LiPA genotyping assay.Comprehensive human virus screening using high-throughput sequencing with a user-friendly representation of bioinformatics analysis: a pilot study Analysis of ultra-deep pyrosequencing and cloning based sequencing of the basic core promoter/precore/core region of hepatitis B virus using newly developed bioinformatics tools.Dynamics of mitochondrial heteroplasmy in three families investigated via a repeatable re-sequencing study.Applications of next-generation sequencing technologies to diagnostic virology.Dengue Virus Evolution under a Host-Targeted Antiviral.Ultradeep Sequencing for Detection of Quasispecies Variants in the Major Hydrophilic Region of Hepatitis B Virus in Indonesian Patients.Complex Genotype Mixtures Analyzed by Deep Sequencing in Two Different Regions of Hepatitis B Virus.Spouse-to-Spouse Transmission and Evolution of Hypervariable Region 1 and 5' Untranslated Region of Hepatitis C Virus Analyzed by Next-Generation Sequencing Hepatitis B virus sub-genotype A1 infection is characterized by high replication levels and rapid emergence of drug resistance in HIV-positive adults receiving first-line antiretroviral therapy in Malawi De novo assembly of highly polymorphic metagenomic data using in situ generated reference sequences and a novel BLAST-based assembly pipeline.Quasispecies dynamics in main core epitopes of hepatitis B virus by ultra-deep-pyrosequencing Aligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus Low-level persistence of drug resistance mutations in hepatitis B virus-infected subjects with a past history of Lamivudine treatment.

P2860

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P2860

Use of massively parallel ultradeep pyrosequencing to characterize the genetic diversity of hepatitis B virus in drug-resistant and drug-naive patients and to detect minor variants in reverse transcriptase and hepatitis B S antigen.

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http://www.wikidata.org/entity/Q37099761

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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