about
Cholesterol loading and ultrastable protein interactions determine the level of tumor marker required for optimal isolation of cancer cellsBeyond picomolar affinities: quantitative aspects of noncovalent and covalent binding of drugs to proteinsElectrophilic affibodies forming covalent bonds to protein targetsRadioimmunotherapy of human tumoursAntibody-targeted radiation cancer therapyBeyond new chemical entities: advancing drug development based on functional versatility of antibodiesRates and equilibria for probe capture by an antibody with infinite affinity.A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst.Successful radiotherapy of tumor in pretargeted mice by 188Re-radiolabeled phosphorodiamidate morpholino oligomer, a synthetic DNA analogue.Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug developmentEnhancing peptide ligand binding to vascular endothelial growth factor by covalent bond formation.Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates.An engineered selenocysteine defines a unique class of antibody derivatives.The chemistry of irreversible capture.Selective labeling of proteins with chemical probes in living cells.Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.An in vivo covalent TMP-tag based on proximity-induced reactivityChemically programmed antibodies.Genetically encoding new bioreactivity.Cysteinylated protein as reactive disulfide: an alternative route to affinity labeling.Covalent labelling of fusion proteins in live cells via an engineered receptor-ligand pair.New covalent capture probes for imaging and therapy, based on a combination of binding affinity and disulfide bond formation.A metalloantibody that irreversibly binds a protein antigen.Single and multiple bonds in (strept)avidin-biotin interactions.Using Protein-Confined Proximity To Determine Chemical Reactivity.Exo-mechanism proximity-accelerated alkylations: investigations of linkers, electrophiles and surface mutations in engineered cyclophilin-cyclosporin systems.Whither Radioimmunotherapy: To Be or Not To Be?Selective two-step labeling of proteins with an off/on fluorescent probe.Chemical Methodology for Labelling and Bioconjugation
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 July 2001
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Antibodies with infinite affinity.
@en
Antibodies with infinite affinity.
@nl
type
label
Antibodies with infinite affinity.
@en
Antibodies with infinite affinity.
@nl
prefLabel
Antibodies with infinite affinity.
@en
Antibodies with infinite affinity.
@nl
P2093
P2860
P356
P1476
Antibodies with infinite affinity.
@en
P2093
P2860
P304
P356
10.1073/PNAS.151260298
P407
P577
2001-07-10T00:00:00Z