Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.
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Methods to Increase the Metabolic Stability of (18)F-RadiotracersNon-invasive anatomic and functional imaging of vascular inflammation and unstable plaqueMicrofluidics: a groundbreaking technology for PET tracer production?PET radiotracers: crossing the blood-brain barrier and surviving metabolismPET imaging of stroke-induced neuroinflammation in mice using [18F]PBR06Fluorine-18 chemistry in micro-reactors.Biodistribution and radiation dosimetry in humans of a new PET ligand, (18)F-PBR06, to image translocator protein (18 kDa).Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline.The relationship between serial [(18) F]PBR06 PET imaging of microglial activation and motor function following stroke in mice.Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.Comparison of 18F- and 11C-labeled aryloxyanilide analogs to measure translocator protein in human brain using positron emission tomography[¹⁸F]FE@SNAP-A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): microfluidic and vessel-based approachesOn quantitative relationships between drug-like compound lipophilicity and plasma free fraction in monkey and human.Quantification of translocator protein (18 kDa) in the human brain with PET and a novel radioligand, (18)F-PBR06.Microfluidics for positron emission tomography probe development.Molecular Imaging of Hypoxia: Strategies for Probe Design and Application.The potential of carbon-11 and fluorine-18 chemistry: illustration through the development of positron emission tomography radioligands targeting the translocator protein 18 kDa.Flow microreactor synthesis in organo-fluorine chemistry.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.Effect of stress and peripheral immune activation on astrocyte activation in transgenic bioluminescent Gfap-luc mice.Use of 3-[(18)F]fluoropropanesulfonyl chloride as a prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamidesPreclinical in vivo and in vitro comparison of the translocator protein PET ligands [18F]PBR102 and [18F]PBR111.A solvent resistant lab-on-chip platform for radiochemistry applications.
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P2860
Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2009
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Single-step high-yield radiosy ...... odiazepine receptors with PET.
@en
Single-step high-yield radiosy ...... odiazepine receptors with PET.
@nl
type
label
Single-step high-yield radiosy ...... odiazepine receptors with PET.
@en
Single-step high-yield radiosy ...... odiazepine receptors with PET.
@nl
prefLabel
Single-step high-yield radiosy ...... odiazepine receptors with PET.
@en
Single-step high-yield radiosy ...... odiazepine receptors with PET.
@nl
P2093
P2860
P356
P1476
Single-step high-yield radiosy ...... zodiazepine receptors with PET
@en
P2093
Emmanuelle Briard
Fabrice G Siméon
H Umesha Shetty
Jonathan P Gourley
Masahiro Fujita
Masao Imaizumi
Robert B Innis
Sami S Zoghbi
Victor W Pike
P2860
P304
P356
10.1021/JM8011855
P407
P50
P577
2009-02-01T00:00:00Z