Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes
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N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes.Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses.Testing for differentially expressed genetic pathways with single-subject N-of-1 data in the presence of inter-gene correlation.Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells.A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations.kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects.Neonatal immune response to rhinovirus A16 has diminished dendritic cell function and increased B cell activation.Impaired type I interferon regulation in the blood transcriptome of recurrent asthma exacerbations.
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Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 March 2015
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Towards a PBMC "virogram assay ...... viral infection transcriptomes
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Towards a PBMC "virogram assay ...... iral infection transcriptomes.
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type
label
Towards a PBMC "virogram assay ...... viral infection transcriptomes
@en
Towards a PBMC "virogram assay ...... iral infection transcriptomes.
@nl
prefLabel
Towards a PBMC "virogram assay ...... viral infection transcriptomes
@en
Towards a PBMC "virogram assay ...... iral infection transcriptomes.
@nl
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Towards a PBMC "virogram assay ...... viral infection transcriptomes
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Anthony Bosco
Daniel Jackson
Fernando D Martinez
Jianrong Li
Marilyn J Halonen
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10.1016/J.JBI.2015.03.003
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2015-03-19T00:00:00Z