Major tegument protein pp65 of human cytomegalovirus is required for the incorporation of pUL69 and pUL97 into the virus particle and for viral growth in macrophages.
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Role of human cytomegalovirus tegument proteins in virion assemblyInhibition of human cytomegalovirus immediate-early gene expression by cyclin A2-dependent kinase activityHuman cytomegaloviruses expressing yellow fluorescent fusion proteins--characterization and use in antiviral screening.Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.Identification of binary interactions between human cytomegalovirus virion proteins.Human cytomegalovirus UL97 kinase and nonkinase functions mediate viral cytoplasmic secondary envelopment.A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism.The Cellular Proteins Grb2 and DDX3 Are Increased upon Human Cytomegalovirus Infection and Act in a Proviral Fashion.Human cytomegalovirus UL97 kinase alters the accumulation of CDK1.The ULb' region of the human cytomegalovirus genome confers an increased requirement for the viral protein kinase UL97.Positive Expression of Human Cytomegalovirus Phosphoprotein 65 in Atherosclerosis.Interaction between HCMV pUL83 and human AIM2 disrupts the activation of the AIM2 inflammasome.Cytomegalovirus pp65 limits dissemination but is dispensable for persistence.Role of tegument proteins in herpesvirus assembly and egress.Human cytomegalovirus tegument proteins (pp65, pp71, pp150, pp28).Highly acidic C-terminal region of cytomegalovirus pUL96 determines its functions during virus maturation independently of a direct pp150 interaction.The proteome of human cytomegalovirus virions and dense bodies is conserved across different strains.Proteomic analyses of human cytomegalovirus strain AD169 derivatives reveal highly conserved patterns of viral and cellular proteins in infected fibroblasts.Nuclear targeting of human cytomegalovirus large tegument protein pUL48 is essential for viral growth.A leucine zipper motif of a tegument protein triggers final envelopment of human cytomegalovirusRegulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability.Differentiation between polymorphisms and resistance-associated mutations in human cytomegalovirus DNA polymerase.Fluorescence-based assay for phenotypic characterization of human cytomegalovirus polymerase mutations regarding drug susceptibility and viral replicative fitness.Human cytomegalovirus triggers the assembly of AIM2 inflammasome in THP-1-derived macrophages.Effectiveness of PCR and Immunofluorescence Techniques for Detecting Human Cytomegalovirus in Blood and Bronchoalveolar Lavage Fluid.Human Cytomegalovirus pUL47 Modulates Tegumentation and Capsid Accumulation at the Viral Assembly Complex.The tegument protein pp65 of human cytomegalovirus acts as an optional scaffold protein that optimizes protein uploading into viral particles.Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation.The tegument protein UL71 of human cytomegalovirus is involved in late envelopment and affects multivesicular bodies.Cytomegalovirus UL103 controls virion and dense body egress.Nucleocytoplasmic shuttling and CRM1-dependent MHC class I peptide presentation of human cytomegalovirus pp65.The Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING.The M25 gene products are critical for the cytopathic effect of mouse cytomegalovirus.A Tyrosine-Based Trafficking Motif of the Tegument Protein pUL71 Is Crucial for Human Cytomegalovirus Secondary Envelopment.The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB Activity
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Major tegument protein pp65 of human cytomegalovirus is required for the incorporation of pUL69 and pUL97 into the virus particle and for viral growth in macrophages.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 30 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Major tegument protein pp65 of ...... r viral growth in macrophages.
@en
Major tegument protein pp65 of ...... r viral growth in macrophages.
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type
label
Major tegument protein pp65 of ...... r viral growth in macrophages.
@en
Major tegument protein pp65 of ...... r viral growth in macrophages.
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prefLabel
Major tegument protein pp65 of ...... r viral growth in macrophages.
@en
Major tegument protein pp65 of ...... r viral growth in macrophages.
@nl
P2093
P2860
P356
P1433
P1476
Major tegument protein pp65 of ...... r viral growth in macrophages.
@en
P2093
Anke Lüske
Christopher Buser
Giada Frascaroli
Jens von Einem
Leonhard Linta
Sandra Landwehr
Thomas Mertens
P2860
P304
P356
10.1128/JVI.01818-08
P407
P577
2008-12-30T00:00:00Z