Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. - Wikidata - wikimedia - TriplyDB

Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.

Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.

http://www.wikidata.org/entity/Q33964039

about

IFI16 is an innate immune sensor for intracellular DNA The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion Intrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escape Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localization Role of human cytomegalovirus tegument proteins in virion assembly Innate immune detection of microbial nucleic acids.Proteomic approaches to uncovering virus-host protein interactions during the progression of viral infection Inflammasome control of viral infection The inflammasome as a target of modulation by DNA viruses Discovery and targeted LC-MS/MS of purified polerovirus reveals differences in the virus-host interactome associated with altered aphid transmission IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications The mammalian PYHIN gene family: phylogeny, evolution and expression A proteomic perspective of inbuilt viral protein regulation: pUL46 tegument protein is targeted for degradation by ICP0 during herpes simplex virus type 1 infection.Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.Mechanism of curcumin resistance to human cytomegalovirus in HELF cells Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA.Quantitative proteomic analysis of host-virus interactions reveals a role for Golgi brefeldin A resistance factor 1 (GBF1) in dengue infection.Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.In vitro study on human cytomegalovirus affecting early pregnancy villous EVT's invasion function.Tegument protein control of latent herpesvirus establishment and animation.Roseomics: a blank slate.Nuclear DNA sensor IFI16 as circulating protein in autoimmune diseases is a signal of damage that impairs endothelial cells through high-affinity membrane binding.Mass spectrometry-based proteomic approaches for discovery of HIV-host interactions.DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection.Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16.The life cycle and pathogenesis of human cytomegalovirus infection: lessons from proteomics Inactivation of the Human Cytomegalovirus US20 Gene Hampers Productive Viral Replication in Endothelial Cells.The emerging role of nuclear viral DNA sensors.Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection.Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions.Recognition of herpesviruses by the innate immune system Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding.Multiple Transcripts Encode Full-Length Human Cytomegalovirus IE1 and IE2 Proteins during Lytic Infection.The tiers and dimensions of evasion of the type I interferon response by human cytomegalovirus.Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection.

P2860

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P2860

Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.

http://www.wikidata.org/entity/Q33964039

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Human cytomegalovirus pUL83 st ...... th the cellular IFI16 protein.

@ast

Human cytomegalovirus pUL83 st ...... th the cellular IFI16 protein.

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type

label

Human cytomegalovirus pUL83 st ...... th the cellular IFI16 protein.

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Human cytomegalovirus pUL83 st ...... th the cellular IFI16 protein.

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prefLabel

Human cytomegalovirus pUL83 st ...... th the cellular IFI16 protein.

@ast

Human cytomegalovirus pUL83 st ...... th the cellular IFI16 protein.

@en

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Human cytomegalovirus pUL83 st ...... ith the cellular IFI16 protein

@en

P2093

Brian T Chait

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Christian D Cuevas

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Erin S O'Keefe

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Ileana M Cristea

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Nathaniel J Moorman

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Scott S Terhune

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Thomas Shenk

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P2860

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

The human interferon-inducible protein, IFI 16, is a repressor of transcription

Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Isotypic variants of the interferon-inducible transcriptional repressor IFI 16 arise through differential mRNA splicing

Inactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expression

Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expression

IFI16 as a negative regulator in the regulation of p53 and p21(Waf1)

Genomic organization of IFI16, an interferon-inducible gene whose expression is associated with human myeloid cell differentiation: correlation of predicted protein domains with exon organization

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

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7803-7814

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scholarly article

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10.1128/JVI.00139-10

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15

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84

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P577

2010-05-26T00:00:00Z

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20504932

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P921

Cytomegalovirus

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2897612

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