Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells
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Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia.Acute myeloid leukemia: advancing clinical trials and promising therapeutics.Ex vivo activity of BCL-2 family inhibitors ABT-199 and ABT-737 combined with 5-azacytidine in myeloid malignanciesBCL-2 family proteins as 5-Azacytidine-sensitizing targets and determinants of response in myeloid malignancies.5-Azacytidine specifically inhibits the NIH-3T3 PCD process induced by TNF-alpha and cycloheximide via affecting BCL-XL.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.Combined venetoclax and alvocidib in acute myeloid leukemia.A concise review of BCL-2 inhibition in acute myeloid leukemia.Clinical experience with the BCL2-inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies.Pathways and mechanisms of venetoclax resistance.Venetoclax: A novel B-cell lymphoma-2 inhibitor for chronic lymphocytic leukemia and other hematologic malignancies.Venetoclax in Combination with Decitabine for Relapsed T-Cell Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Cell Transplant
P2860
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P2860
Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 15 August 2012
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Concomitant inhibition of DNA ...... ute myelogenous leukemia cells
@en
Concomitant inhibition of DNA ...... te myelogenous leukemia cells.
@nl
type
label
Concomitant inhibition of DNA ...... ute myelogenous leukemia cells
@en
Concomitant inhibition of DNA ...... te myelogenous leukemia cells.
@nl
prefLabel
Concomitant inhibition of DNA ...... ute myelogenous leukemia cells
@en
Concomitant inhibition of DNA ...... te myelogenous leukemia cells.
@nl
P2093
P2860
P50
P921
P1433
P1476
Concomitant inhibition of DNA ...... ute myelogenous leukemia cells
@en
P2093
Ansu Antony
Kensuke Kojima
Ninaxiang Zhang
Sergej Konoplev
Steven Kornblau
Vivian Ruvolo
Yi Hua Qiu
P2860
P304
P356
10.1007/S00277-012-1537-8
P577
2012-08-15T00:00:00Z