Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity.
about
Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait lociPharmacogenomics of chemotherapeutic susceptibility and toxicityPharmacogenomic discovery using cell-based modelsComprehensive survey of SNPs in the Affymetrix exon array using the 1000 Genomes datasetProtein quantitative trait loci identify novel candidates modulating cellular response to chemotherapyPolymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies.Methods of integrating data to uncover genotype-phenotype interactions.An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers.Impact of the 1000 genomes project on the next wave of pharmacogenomic discoveryImpact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia.Population-specific common SNPs reflect demographic histories and highlight regions of genomic plasticity with functional relevanceGenome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.Integrating heterogeneous high-throughput data for meta-dimensional pharmacogenomics and disease-related studiesHeritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.Genetics of human gene expression: mapping DNA variants that influence gene expression.Population differences in the rate of proliferation of international HapMap cell lines.The use of genomic information to optimize cancer chemotherapyA genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.Lymphoblastoid cell lines models of drug response: successes and lessons from this pharmacogenomic model.Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes.Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia.Population differences in microRNA expression and biological implications.The emerging role of microRNAs in drug responsesLymphoblastoid cell lines in pharmacogenomic discovery and clinical translationBioinformatic Resources of microRNA Sequences, Gene Targets, and Genetic Variation.Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral NeuropathyIdentification of novel germline polymorphisms governing capecitabine sensitivity.Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.Genetic and epigenetic variants contributing to clofarabine cytotoxicity.RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients.Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy.Use of cell lines in the investigation of pharmacogenetic loci.Genetic factors influencing cytarabine therapy.An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia.Genome-wide transcriptomic variations of human lymphoblastoid cell lines: insights from pairwise gene-expression correlations.SLC29A1 (ENT1) polymorphisms and outcome of complete remission in acute myeloid leukemia.Analysis of innate and acquired resistance to anti-CD20 antibodies in malignant and nonmalignant B cellsGenome-wide miRNA expression profiling of human lymphoblastoid cell lines identifies tentative SSRI antidepressant response biomarkers.
P2860
Q24631841-853CA357-028B-4283-9587-4126A11471EAQ27025558-4D5D9C9C-237B-45E9-9257-12123E198BFAQ28392982-B5881E1E-AA36-47F3-A19C-936E1ACD699CQ28472992-B47E9E16-88D3-4439-8617-6CFB19C78739Q28541831-8A1D05AE-41C7-46A2-9E47-DD4CCD001784Q30244222-F8E12C20-CBD9-44E0-88D8-4D89BECD2D46Q30884207-4BDB31A2-02C4-4950-9525-AF78760E0C2EQ33398764-D6921BAF-C514-42D4-9AF4-57C8F5AA81CAQ33708200-A09C2D04-CE35-4EC3-8239-FC163C01A22DQ33799305-966DE0A1-8CB8-47D4-AA50-ACE74F2F4F64Q33883099-FE585E9E-AA29-4148-94FB-A2E4DB677861Q33960326-5874339E-21C0-4817-86CA-BD22FDC379EAQ34132233-450D8611-5B13-4199-A233-6471C4F28E05Q34288272-BA6D465A-51A7-4AB9-98DD-EB87272BFCDAQ34339168-07533E9C-0675-4641-A6B7-9B7F567CA3BDQ34381762-14824736-54C2-4C2A-9FA8-A601C1C32296Q34791981-D130BB0B-821D-44FA-935E-AE6B677484D0Q34989475-3E5D4CE1-FB26-4925-BACB-C1F01BAEEE07Q35068272-C01A0743-EFC5-450D-91D9-9EFE90DDFED6Q35099987-F0B53A88-6E06-4B3A-A33F-BE1488B687CCQ35114704-335EB040-6FF6-41B7-9368-63B88D369445Q35265653-CC9E7830-0D71-4465-92B8-F332753E4E5FQ35578546-85C47F34-2720-47EE-BEF9-F69F0C348D27Q35599477-9E6BBD9B-1708-4082-9A3D-8C988B2FEF46Q35799841-83F5BAF2-3B63-4D1A-AE56-1B4124B85724Q35800946-4C4666EB-886F-405F-8303-E143C3220277Q36117686-0B424B1B-EEC9-463D-B75B-BB377297A84AQ36147462-CDB37B7D-4F39-4360-AE9D-D47305ADE77BQ36873301-A72BE6D6-1B0B-483D-9338-396F3A18DAA4Q37153800-4CD71EE7-4BA1-498C-9BB4-B77D82735928Q37387162-D8790182-3CE8-4E08-8D7C-4E10568B479CQ37414536-B7E7EE10-5E4B-462C-A4C6-19480A77C88BQ37436398-3F5D0A1D-8A20-46B5-B65B-648BDC2599AFQ37618228-BB5848EA-3530-4D15-B68D-4D683F1D85A0Q37855227-CBA8230B-1BC6-4EFB-BBFC-1A0DA736D353Q38063197-DD3DE944-E821-4180-904D-F407D276B9A5Q38319500-B21BD518-3BCB-4B09-B3C0-F4EF1217D644Q38757910-4EFD6A47-BF87-4EA5-A78B-B1C0B8BD32FAQ39157250-6A242C8E-5DC2-43F3-9763-B15D5D4B5435Q39293823-6DC589B6-B095-4118-B001-30B5D253A5FF
P2860
Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Population-specific genetic va ...... bine arabinoside cytotoxicity.
@en
Population-specific genetic va ...... bine arabinoside cytotoxicity.
@nl
type
label
Population-specific genetic va ...... bine arabinoside cytotoxicity.
@en
Population-specific genetic va ...... bine arabinoside cytotoxicity.
@nl
prefLabel
Population-specific genetic va ...... bine arabinoside cytotoxicity.
@en
Population-specific genetic va ...... bine arabinoside cytotoxicity.
@nl
P2093
P2860
P1433
P1476
Population-specific genetic va ...... abine arabinoside cytotoxicity
@en
P2093
Christine M Hartford
Emily O Kistner
Jatinder K Lamba
M Eileen Dolan
Shannon M Delaney
Shiwei Duan
Shuangli Mi
P2860
P304
P356
10.1182/BLOOD-2008-05-154302
P407
P577
2008-12-24T00:00:00Z