Adaptation-based resistance to siderophore-conjugated antibacterial agents by Pseudomonas aeruginosa
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Trojan Horse Antibiotics-A Novel Way to Circumvent Gram-Negative Bacterial Resistance?Targeting virulence: salmochelin modification tunes the antibacterial activity spectrum of β-lactams for pathogen-selective killing of Escherichia coli.Pseudomonas fluorescens pirates both ferrioxamine and ferricoelichelin siderophores from Streptomyces ambofaciens.Evaluation of Gallium Citrate Formulations against a Multidrug-Resistant Strain of Klebsiella pneumoniae in a Murine Wound Model of Infection.Iron acquisition in the cystic fibrosis lung and potential for novel therapeutic strategies.Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated EfficacyCharacterization of microbial siderophores by mass spectrometry.Translational deficiencies in antibacterial discovery and new screening paradigms.What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles.Bifunctional antimicrobial conjugates and hybrid antimicrobials.Urinary Concentrations and Antibacterial Activity of BAL30072, a Novel Siderophore Monosulfactam, against Uropathogens after Intravenous Administration in Healthy Subjects.Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development.Potentiation of antibacterial activity of the MB-1 siderophore-monobactam conjugate using an efflux pump inhibitorSiderophore Cephalosporin Cefiderocol Utilizes Ferric Iron Transporter Systems for Antibacterial Activity against Pseudomonas aeruginosa.Enterobactin-mediated delivery of β-lactam antibiotics enhances antibacterial activity against pathogenic Escherichia coli.In vitro antibacterial properties of cefiderocol, a novel siderophore cephalosporin, against Gram-negative bacteria.Facile and Versatile Chemoenzymatic Synthesis of Enterobactin Analogues and Applications in Bacterial Detection.In Vitro Activity of the Siderophore Cephalosporin, Cefiderocol, against a Recent Collection of Clinically Relevant Gram-Negative Bacilli from North America and Europe, Including Carbapenem-Nonsusceptible Isolates (SIDERO-WT-2014 Study).Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa.Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity.In vitro antimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria.
P2860
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P2860
Adaptation-based resistance to siderophore-conjugated antibacterial agents by Pseudomonas aeruginosa
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 17 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Adaptation-based resistance to ...... ents by Pseudomonas aeruginosa
@en
Adaptation-based resistance to ...... nts by Pseudomonas aeruginosa.
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type
label
Adaptation-based resistance to ...... ents by Pseudomonas aeruginosa
@en
Adaptation-based resistance to ...... nts by Pseudomonas aeruginosa.
@nl
prefLabel
Adaptation-based resistance to ...... ents by Pseudomonas aeruginosa
@en
Adaptation-based resistance to ...... nts by Pseudomonas aeruginosa.
@nl
P2093
P2860
P356
P1476
Adaptation-based resistance to ...... ents by Pseudomonas aeruginosa
@en
P2093
Andrew P Tomaras
Craig J McPherson
David P Nicolau
Jared L Crandon
John P O'Donnell
Mary Anne Banevicius
Matthew F Brown
Rebecca L Irvine
Steven M Finegan
P2860
P304
P356
10.1128/AAC.00629-13
P407
P577
2013-06-17T00:00:00Z