Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1 - Wikidata - wikimedia - TriplyDB

Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1

Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1

http://www.wikidata.org/entity/Q37124999

about

HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor Alcoholic liver disease: pathogenesis and new therapeutic targets.Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein Cellular functions of tissue transglutaminase Gliadin peptides induce tissue transglutaminase activation and ER-stress through Ca2+ mobilization in Caco-2 cells Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data.Opposing effects of two tissue transglutaminase protein isoforms in neuroblastoma cell differentiation.Transglutaminase regulation of cell function.Fungus-derived hydroxyl radicals kill hepatic cells by enhancing nuclear transglutaminase.Transglutaminase 2 inhibits apoptosis induced by calcium- overload through down-regulation of Bax Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells.Characterization of distinct sub-cellular location of transglutaminase type II: changes in intracellular distribution in physiological and pathological states Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis.Transglutaminase 2: a molecular Swiss army knife.Tissue Transglutaminase-Regulated Transformed Growth Factor-β1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis.Keratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory-Denk body formation.Changes in mitochondrial DNA and its encoded products in alcoholic cirrhosis.Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells Lamin aggregation is an early sensor of porphyria-induced liver injury Variations in both TG1 and TG2 isozyme-specific in situ activities and protein expressions during mouse embryonic development Transglutaminse 2 and EGGL, the protein cross-link formed by transglutaminse 2, as therapeutic targets for disabilities of old age.Recent advances in understanding the roles of transglutaminase 2 in alcoholic steatohepatitis.Induction of cross-linking and silencing of Sp1 by transglutaminase during liver injury in ASH and NASH via different ER stress pathways.TG2, a novel extracellular protein with multiple functions.New insights into the functions and localization of nuclear transglutaminase 2.Tissue Transglutaminase (TG2)-Induced Inflammation in Initiation, Progression, and Pathogenesis of Pancreatic Cancer.Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target.Sp1 and the 'hallmarks of cancer'.Moonlighting proteins in cancer.Transglutaminase-catalyzed incorporation of polyamines masks the DNA-binding region of the transcription factor Relish.Mechanism of Hepatocyte Apoptosis.In situ detection of active transglutaminases for keratinocyte type (TGase 1) and tissue type (TGase 2) using fluorescence-labeled highly reactive substrate peptides.Pituitary adenylate cyclase-activating polypeptide type 1 receptor (PAC1) gene is suppressed by transglutaminase 2 activation.SP and KLF Transcription Factors in Digestive Physiology and Diseases.Inhibition of tissue transglutaminase sensitizes TRAIL-resistant lung cancer cells through upregulation of death receptor 5.Global identification and analysis of isozyme-specific possible substrates crosslinked by transglutaminases using substrate peptides in mouse liver fibrosis Transglutaminase 2 facilitates or ameliorates HIF signaling and ischemic cell death depending on its conformation and localization.Norepinephrine modulates the zonally different hepatocyte proliferation through the regulation of transglutaminase activity.

P2860

Q24308693-AE2B7B29-810B-4E93-B9CE-47FD9FB2C334 Q27690220-A222578D-D7A1-49EC-91D3-7EE26510B9DC Q28069852-C5CDC1B0-9598-40ED-8D87-711941EE219A Q28247511-FF85C42B-D399-40A3-A1BB-1C099F07ABCE Q28260600-EE1ACCD9-02DA-4EFC-8188-4CB84D041039 Q28484010-90C1E03A-1F24-4190-8817-3596668CC3EE Q33538943-74288EED-C03C-4915-979E-AC213F450CF5 Q33661950-A908A3BC-615B-443A-A317-6ECFAC625143 Q33707936-8DE4992C-1193-48C9-A330-61695BFE6999 Q33881464-3B3ED004-447D-4C76-812B-40C3CDD9B1CD Q34161250-6F75D932-F77E-4814-9E92-272A6304DBD0 Q34506882-3F553E90-5715-4CAF-A1EA-4BF37202BE99 Q34517980-8CDEB3D2-C742-4FB9-8C63-BA193CEF7260 Q34743269-008ADFF9-A1AA-4D48-818A-C014EF980B42 Q35131965-C2F574F0-16F6-476B-AE9E-223C49913B7A Q35693361-75D58D11-606D-47CA-875F-8C09CA120D0D Q35823916-3C1D8FB3-E6C1-4926-BC86-4FB6C724E9E0 Q35987918-54C69FA3-EBB6-4F05-A31A-630DECBDFEA4 Q36111630-63C2F748-6E61-4A3A-8615-08D653E71744 Q36485122-407D7530-8568-4C48-B56D-7568D709789E Q37012014-08959F9B-1191-48DB-8EC8-1AA96852ECB2 Q37255857-7318765F-E47B-41A6-9657-A4503E49EF89 Q37406648-32C926C1-6C67-40A1-913D-74C45D9D86F7 Q37700761-D11B2829-8C02-486F-8931-922B0E016E62 Q37869760-D4103994-BE2E-42A3-9F34-F85C993C6AEB Q37912042-E97A3106-4A7E-4A67-B88F-BDDA9A7C261A Q37952438-A442EBD6-F85B-46AB-8DFF-304FDCECFCA9 Q38161340-FBC48305-3DF7-40A6-824B-CD70F8CB14C2 Q38209122-26D8E28E-F118-42A5-9388-0217B22FC7FB Q38267908-B38BD660-43C7-4647-B9B7-FB30E36118A8 Q38616107-285974AB-FF53-496C-BBA9-269FE87A7462 Q38713951-82A00980-DEC2-48EE-9A17-82BDCAAAD1D9 Q38774266-EF641768-93A8-4A55-BC28-2D18AF2BEE8C Q38819973-85D47F32-9071-481D-AD80-E093CFC0A496 Q39094479-F912F9DF-952C-4F9E-AA2A-9854C85577EC Q39214035-5BA28C5C-D5D2-41CA-A7C7-20AA6774B9F7 Q39706496-FABA3BE0-1D8B-4B2C-BE5D-3F8073E319B1 Q42241587-27A3ABE0-366B-4546-B4A8-1F7010DF6AFA Q42403952-29DC0905-48E1-464E-83AF-7D42499AF871 Q43071472-D294C1E7-D142-46E2-9E5A-3684AB5717CC

P2860

Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1

http://www.wikidata.org/entity/Q37124999

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 14 January 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Role of transglutaminase 2 in ...... ng of transcription factor Sp1

@en

Role of transglutaminase 2 in ...... g of transcription factor Sp1.

@nl

type

label

Role of transglutaminase 2 in ...... ng of transcription factor Sp1

@en

Role of transglutaminase 2 in ...... g of transcription factor Sp1.

@nl

prefLabel

Role of transglutaminase 2 in ...... ng of transcription factor Sp1

@en

Role of transglutaminase 2 in ...... g of transcription factor Sp1.

@nl

P1433

Q37124999-3AA9B8B3-31C6-460C-9B00-3A1A1883FF45

P1476

Q37124999-5F65BBAE-49A2-49EF-B748-F04C08FAE2B9

P2093

Q37124999-1BA63057-4DF4-4E5A-A8CC-C864156B2A0B

Q37124999-1E6B3396-8082-4E23-801B-5D66E4AC51AD

Q37124999-3543CE3D-65B2-40FD-B729-B5DBB3B80588

Q37124999-4DAFF968-277F-405F-A8E5-5FD1E81DA7ED

Q37124999-672AAABF-86D2-4B0C-8C22-9F1CE84CE17A

Q37124999-6F03AD6E-2276-4257-B0D0-0F3998BE562E

Q37124999-6FFD3FB9-FAC6-4D9C-924D-AF8B073D93C7

Q37124999-93BD6181-98CA-49E0-9DB9-F26369972A0C

Q37124999-D469878A-87F8-4C14-BD67-B3EE31C08422

Q37124999-D754C6CE-E79B-4385-B40E-1F103A95CC52

P2860

Q37124999-069DCA26-68AC-4BEF-83AE-313B9FAC9886

Q37124999-0F7EE7A6-7556-4170-98AC-A2699EDA1078

Q37124999-2296B8E3-57C7-4422-A776-993473D0B150

Q37124999-363C4A5B-C6C3-482F-9401-CEC4A1329925

Q37124999-38608B27-F9DE-4116-A535-8B2AAD71CBC9

Q37124999-3EAB9AEE-A637-4C7A-92B4-E31551DA9870

Q37124999-4DC11E2C-0102-476A-A620-D56AA60369B9

Q37124999-4E652F14-9DDF-4838-B667-DE39DD3832AD

Q37124999-571500D0-E816-404C-A8F6-63FA74CAD9B8

Q37124999-5CF788E9-21DD-4FBB-A749-6F2BA05C5658

P304

Q37124999-FF479C85-8A84-46AE-80FD-82925407A978

P31

Q37124999-EC3539A8-344A-4519-9C1D-2AACF6D1E02E

P356

Q37124999-7EB0FD2B-D5D5-452E-9528-45448DA7A290

P407

Q37124999-4F3006BF-B75F-4059-B1D0-BAF194B076A8

P433

Q37124999-6D98C613-B621-444C-9BEF-F12DC064DD4F

P478

Q37124999-74BF5667-C1BB-43E9-8A28-63E380788460

P50

Q37124999-45B63449-1D74-4938-84FE-26CFC216F838

Q37124999-A04B2D81-84A1-4632-AAE2-816715976C1B

P577

Q37124999-EC23C10C-5014-4FB1-A517-E2FC3BDEDB7F

P5875

Q37124999-4E61F914-D86D-43AD-855D-FEC5D12F4A65

P698

Q37124999-E15286DD-D7E3-448A-A61D-B67E3093FD62

P932

Q37124999-B2450002-C6FB-491F-ABA9-EFAC1BABCE4D

P356

J.GASTRO.2009.01.007

P1433

Gastroenterology

P1476

Role of transglutaminase 2 in ...... ng of transcription factor Sp1

@en

P2093

Antonio Martinez-Fuentes

http://www.w3.org/2001/XMLSchema#string

Gordon Frampton

http://www.w3.org/2001/XMLSchema#string

Hidekazu Tsukamoto

http://www.w3.org/2001/XMLSchema#string

Hideki Tatsukawa

http://www.w3.org/2001/XMLSchema#string

Jian Wu

http://www.w3.org/2001/XMLSchema#string

Keisuke Nagatsuma

http://www.w3.org/2001/XMLSchema#string

Kenji Suzuki

http://www.w3.org/2001/XMLSchema#string

Kentaro Shimokado

http://www.w3.org/2001/XMLSchema#string

Mark A Zern

http://www.w3.org/2001/XMLSchema#string

Masataka Okuno

http://www.w3.org/2001/XMLSchema#string

P2860

Transglutaminases: nature's biological glues

Interaction of Huntington disease protein with transcriptional activator Sp1

Intron-exon swapping of transglutaminase mRNA and neuronal Tau aggregation in Alzheimer's disease

Transglutaminase 2: an enigmatic enzyme with diverse functions

Transcriptional activation of endoglin and transforming growth factor-beta signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury

Targeted inactivation of Gh/tissue transglutaminase II

Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction.

The human hepatocyte growth factor receptor gene: complete structural organization and promoter characterization.

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.

Transglutaminases: crosslinking enzymes with pleiotropic functions.

P304

1783-95.e10

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1053/J.GASTRO.2009.01.007

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

136

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-01-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23998758

http://www.w3.org/2001/XMLSchema#string

P698

19208340

http://www.w3.org/2001/XMLSchema#string

P932

4960455

http://www.w3.org/2001/XMLSchema#string