To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications
about
Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.Transforming growth factor-β1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts.Murine protein serine/threonine kinase 38 stimulates TGF-beta signaling in a kinase-dependent manner via direct phosphorylation of Smad proteins.Regulation of Krüppel-like factor 4 by the anaphase promoting complex pathway is involved in TGF-beta signaling.Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-β-mediated growth inhibition.CCN2 requires TGF-β signalling to regulate CCAAT/enhancer binding proteins and inhibit fat cell differentiation.Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells.TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cellsTACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling.Phospho-control of TGF-beta superfamily signaling.Regulation of TGF-beta signalling by protein phosphatases.The TGFbeta superfamily signaling pathway.Yin Yang 1 (YY1) synergizes with Smad7 to inhibit TGF-β signaling in the nucleus.STORE OPERATED CALCIUM ENTRY SUPPRESSED TGFβ1-SMAD3 SIGNALING PATHWAY IN GLOMERULAR MESANGIAL CELLS.Expression of USP15, TβR-I and Smad7 in psoriasis.c-Jun N-terminal kinase 1 negatively regulates osteoblastic differentiation induced by BMP2 via phosphorylation of Runx2 at Ser104.Activation of c-Jun NH(2)-terminal kinase 1 increases cellular responsiveness to BMP-2 and decreases binding of inhibitory Smad6 to the type 1 BMP receptor.SKI promotes Smad3 linker phosphorylations associated with the tumor-promoting trait of TGFbeta.Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription.SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells.
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P2860
To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 February 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
To (TGF)beta or not to (TGF)be ...... st-translational modifications
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To
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type
label
To (TGF)beta or not to (TGF)be ...... st-translational modifications
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To
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prefLabel
To (TGF)beta or not to (TGF)be ...... st-translational modifications
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To
@nl
P2860
P1433
P1476
To (TGF)beta or not to (TGF)be ...... st-translational modifications
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P2093
Katharine H Wrighton
Xin-Hua Feng
P2860
P304
P356
10.1016/J.CELLSIG.2008.02.003
P577
2008-02-15T00:00:00Z