Src as a potential therapeutic target in non-small-cell lung cancer.
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The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasisA robust tool for discriminative analysis and feature selection in paired samples impacts the identification of the genes essential for reprogramming lung tissue to adenocarcinomaSrc kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cellsInitiation factor eIF2-independent mode of c-Src mRNA translation occurs via an internal ribosome entry site.Integrin alpha9beta1: Unique signaling pathways reveal diverse biological roles.Bioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancerLung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformationSrc mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cellsSrc family kinases and paclitaxel sensitivity.Immunohistochemical Characterization of Three Monoclonal Antibodies Raised against the Epidermal Growth Factor and Its Receptor in Non-Small-Cell Lung Cancer: Their Potential Use in the Selection of Patients for ImmunotherapyTargeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer.Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epitheliumRhodomycin A, a novel Src-targeted compound, can suppress lung cancer cell progression via modulating Src-related pathways.Src, p130Cas, and Mechanotransduction in Cancer CellsInsulin-like growth factor-1 receptor-targeted therapy for non-small cell lung cancer: a mini reviewIonizing radiation and glioblastoma exosomes: implications in tumor biology and cell migrationLoss of connectivity in cancer co-expression networks.Dasatinib in solid tumors.SRC kinase is a novel therapeutic target in lymphangioleiomyomatosis.Preclinical pharmacodynamic evaluation of drug candidate SKLB-178 in the treatment of non-small cell lung cancer.Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies.Lysyl oxidase may play a critical role in hypoxia-induced NSCLC cells invasion and migration.Expression and pharmacological inhibition of thymidylate synthase and Src kinase in nonsmall cell lung cancer.The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells.The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulatorc-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells.Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism.Src activation decouples cell division orientation from cell geometry in mammalian cells.Target therapy: new drugs or new combinations of drugs in malignant pleural mesothelioma.[Effects of Src on proliferation and invasion of lung cancer cells].Theoretical Studies on Pyrazolo[3,4-d]pyrimidine Derivatives as Potent Dual c-Src/Abl Inhibitors Using 3D-QSAR and Docking Approaches.YAP and TAZ in Lung Cancer: Oncogenic Role and Clinical Targeting.Molecular mechanism of action and potential biomarkers of growth inhibition of synergistic combination of afatinib and dasatinib against gefitinib-resistant non-small cell lung cancer cells.Src Promotes Metastasis of Human Non-Small Cell Lung Cancer Cells through Fn14-Mediated NF-κB Signaling.Tumor Expression of the Carcinoembryonic Antigen Correlates with High Mitotic Activity and Cell Pleomorphism Index in Lung CarcinomaFlow Cytometric Measurement of Aneuploid DNA Content Correlates with High S-Phase Fraction and Poor Prognosis in Patients with Non-Small-Cell Lung CancerTissue Expression of Low and High Molecular Weight Cytokeratins in Lung Carcinoma Sections: Its Correlation with Some Clinic-Pathological Features
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Src as a potential therapeutic target in non-small-cell lung cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 03 April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Src as a potential therapeutic target in non-small-cell lung cancer.
@en
Src as a potential therapeutic target in non-small-cell lung cancer.
@nl
type
label
Src as a potential therapeutic target in non-small-cell lung cancer.
@en
Src as a potential therapeutic target in non-small-cell lung cancer.
@nl
prefLabel
Src as a potential therapeutic target in non-small-cell lung cancer.
@en
Src as a potential therapeutic target in non-small-cell lung cancer.
@nl
P2860
P356
P1433
P1476
Src as a potential therapeutic target in non-small-cell lung cancer
@en
P2093
P A Zucali
P2860
P304
P356
10.1093/ANNONC/MDN048
P577
2008-04-03T00:00:00Z