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Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanismHematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cellsDistinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASPThe 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and functionA cell-based high-content screening assay reveals activators and inhibitors of cancer cell invasionCortactin branches out: roles in regulating protrusive actin dynamicsMultiparametric classification links tumor microenvironments with tumor cell phenotypeCortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistenceGene expression of human lung cancer cell line CL1-5 in response to a direct current electric fieldCofilin-1 and Other ADF/Cofilin Superfamily Members in Human Malignant CellsRegulation of invasive behavior by vascular endothelial growth factor is HEF1-dependentNEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner.Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanismsConstrained inference of protein interaction networks for invadopodium formation in cancerpTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1)Src-mediated phosphorylation of mammalian Abp1 (DBNL) regulates podosome rosette formation in transformed fibroblastsFAK competes for Src to promote migration against invasion in melanoma cells.Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulationCortactin is involved in the entry of Coxiella burnetii into non-phagocytic cells.The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreadingFurther insights into cortactin conformational regulationCortactin controls cell motility and lamellipodial dynamics by regulating ECM secretionp140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency.HER2 carboxyl-terminal fragments regulate cell migration and cortactin phosphorylationProtein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin.5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers.Cortactin is implicated in murine zygotic development.Cytoskeleton alterations in melanoma: aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression.Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemiaSaracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia FunctionHax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration.Cortactin modulates RhoA activation and expression of Cip/Kip cyclin-dependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells.Cortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading.SYK allelic loss and the role of Syk-regulated genes in breast cancer survival.Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodiaRab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells.Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanomaCalreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cortactin in tumor invasiveness.
@en
Cortactin in tumor invasiveness.
@nl
type
label
Cortactin in tumor invasiveness.
@en
Cortactin in tumor invasiveness.
@nl
prefLabel
Cortactin in tumor invasiveness.
@en
Cortactin in tumor invasiveness.
@nl
P2860
P1433
P1476
Cortactin in tumor invasiveness.
@en
P2860
P304
P356
10.1016/J.CANLET.2008.02.066
P407
P577
2008-04-10T00:00:00Z