Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.
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Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasionCleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partnersVoltage-gated sodium channels and cancer: is excitability their primary role?Ion channels and transporters in tumour cell migration and invasionIon Channels in Brain MetastasisSodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the CPRD primary care databaseExposure to sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the QResearch primary care databaseCancer: fundamentals behind pH targeting and the double-edged approachVoltage-gated sodium channel Nav 1.5 contributes to astrogliosis in an in vitro model of glial injury via reverse Na+ /Ca2+ exchange.Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization.Is there a role for voltage-gated Na+ channels in the aggressiveness of breast cancer?Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasionThe sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.Angiogenic functions of voltage-gated Na+ Channels in human endothelial cells: modulation of vascular endothelial growth factor (VEGF) signaling.Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonizationActivity of plasma membrane V-ATPases is critical for the invasion of MDA-MB231 breast cancer cells.The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis.Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development.Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling.Therapeutic potential for phenytoin: targeting Na(v)1.5 sodium channels to reduce migration and invasion in metastatic breast cancer.The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.Voltage-gated sodium channels and metastatic disease.Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cellsNav1.5 regulates breast tumor growth and metastatic dissemination in vivoA review of the literature on cardiac electrical activity between fibroblasts and myocytes.Na(+) Micro-Current Value Detection as a New Modality for Identification of Benign and Malignant Disease in Surgery.The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells.Cathepsins and their endogenous inhibitors cystatins: expression and modulation in multiple sclerosisExpression profiling of ion channel genes predicts clinical outcome in breast cancer.SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancerCatalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells.Biology of cardiac sodium channel Nav1.5 expression.Roles of ion transport in control of cell motility.The sigma-1 receptor: a regulator of cancer cell electrical plasticity?Regulation of voltage-gated sodium channel expression in cancer: hormones, growth factors and auto-regulation.Dual roles of voltage-gated sodium channels in development and cancer.Involvement of ion channels and transporters in carcinoma angiogenesis and metastasis.Comparison of fluorescence probes for intracellular sodium imaging in prostate cancer cell linesVoltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1.Sodium channels in astroglia and microglia.
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P2860
Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Voltage-gated Sodium Channel A ...... Growth of Human Cancer Cells.
@en
Voltage-gated Sodium Channel A ...... Growth of Human Cancer Cells.
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type
label
Voltage-gated Sodium Channel A ...... Growth of Human Cancer Cells.
@en
Voltage-gated Sodium Channel A ...... Growth of Human Cancer Cells.
@nl
prefLabel
Voltage-gated Sodium Channel A ...... Growth of Human Cancer Cells.
@en
Voltage-gated Sodium Channel A ...... Growth of Human Cancer Cells.
@nl
P2093
P2860
P50
P356
P1476
Voltage-gated Sodium Channel A ...... y Growth of Human Cancer Cells
@en
P2093
Jacques Gore
Jean-Yves Le Guennec
Pierre Besson
P2860
P304
P356
10.1074/JBC.M806891200
P407
P577
2009-01-28T00:00:00Z