Lesion processing: high-fidelity versus lesion-bypass DNA polymerases
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Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencingInhibition of translesion DNA polymerase by archaeal reverse gyraseImpact of Conformational Heterogeneity of OxoG Lesions and Their Pairing Partners on Bypass Fidelity by Y Family PolymerasesMolecular Basis of Transcriptional Mutagenesis at 8-OxoguanineMechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4Structure and mechanism of human DNA polymerase ηImplications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C LesionsBinary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesionThe Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognitionStructural and mechanistic studies of polymerase bypass of phenanthriplatin DNA damageThe N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesionsPolymerase-tailored variations in the water-mediated and substrate-assisted mechanism for nucleotidyl transfer: insights from a study of T7 DNA polymerase.Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion.DNA interstrand crosslink repair in mammalian cells: step by step.DNA binding strength increases the processivity and activity of a Y-Family DNA polymeraseVisualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase.Structural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity.Real-time surface plasmon resonance study of biomolecular interactions between polymerase and bulky mutagenic DNA lesions.DNA pol λ's extraordinary ability to stabilize misaligned DNA.The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/Rev1-dependent translesion DNA synthesis.DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA.Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.Quantitation of DNA adducts by stable isotope dilution mass spectrometry.DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cellsNucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment.Fidelity in archaeal information processing.RB69 DNA polymerase mutants with expanded nascent base-pair-binding pockets are highly efficient but have reduced base selectivity.Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides.Cooperative motion of a key positively charged residue and metal ions for DNA replication catalyzed by human DNA Polymerase-η.Inhibiting translesion DNA synthesis as an approach to combat drug resistance to DNA damaging agents.Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1.Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicityDNA repair: How to accurately bypass damage.Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.Primer-Independent DNA Synthesis by a Family B DNA Polymerase from Self-Replicating Mobile Genetic Elements.Computational Simulations of DNA Polymerases: Detailed Insights on Structure/Function/Mechanism from Native Proteins to Cancer Variants.
P2860
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P2860
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 11 April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases
@en
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases.
@nl
type
label
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases
@en
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases.
@nl
prefLabel
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases
@en
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases.
@nl
P2093
P2860
P1476
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases
@en
P2093
Dinshaw J Patel
Lihua Wang
Nicholas E Geacintov
Olga Rechkoblit
Suse Broyde
P2860
P304
P356
10.1016/J.TIBS.2008.02.004
P577
2008-04-11T00:00:00Z