Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells
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DOCK8 deficiency impairs CD8 T cell survival and function in humans and miceThymic selection generates a large T cell pool recognizing a self-peptide in humansLife and death of lymphocytes: a role in immunesenescenceThe Role of Lymphatic Niches in T Cell DifferentiationNew Insights into the Generation of CD4 Memory May Shape Future Vaccine Strategies for InfluenzaThe Timing of T Cell Priming and CyclingModulation of T Cell Metabolism and Function through Calcium SignalingRegulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses.Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasitesBiologically-directed modeling reflects cytolytic clearance of SIV-infected cells in vivo in macaquesLimited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL EscapeCollateral Damage: Detrimental Effect of Antibiotics on the Development of Protective Immune MemoryListeria monocytogenes: a model pathogen to study antigen-specific memory CD8 T cell responsesDecay kinetics of an interferon gamma release assay with anti-tuberculosis therapy in newly diagnosed tuberculosis casesEffects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized TrialModelling and Simulation of the Dynamics of the Antigen-Specific T Cell Response Using Variable Structure Control TheoryTiming of CD8 T cell effector responses in viral infectionsSecondary T cell–T cell synaptic interactions drive the differentiation of protective CD8+ T cellsCD70 and IFN-1 selectively induce eomesodermin or T-bet and synergize to promote CD8+ T-cell responses.Vaccination by delayed treatment of infection.The cell cycle time of CD8+ T cells responding in vivo is controlled by the type of antigenic stimulus.Proliferative expansion and acquisition of effector activity by memory CD4+ T cells in the lungs following pulmonary virus infectionIn situ imaging of the endogenous CD8 T cell response to infection.Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number.Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsetsHigh epitope expression levels increase competition between T cellsAn IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T cell proliferation.High-throughput gene expression profiling of memory differentiation in primary human T cells.Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.Immunization with single-cycle SIV significantly reduces viral loads after an intravenous challenge with SIV(mac)239.Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells.Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy.Selectively reduced intracellular proliferation of Salmonella enterica serovar typhimurium within APCs limits antigen presentation and development of a rapid CD8 T cell response.Pathogen proliferation governs the magnitude but compromises the function of CD8 T cellsDelayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium.IFN-gamma induces the erosion of preexisting CD8 T cell memory during infection with a heterologous intracellular bacteriumA reduced antigen load in vivo, rather than weak inflammation, causes a substantial delay in CD8+ T cell priming against Mycobacterium bovis (bacillus Calmette-Guérin).Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hostsAdjuvanted influenza vaccine administered intradermally elicits robust long-term immune responses that confer protection from lethal challenge.Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice.
P2860
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P2860
Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2001
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Memory CD8+ T cell differentia ...... pmental program in naïve cells
@en
Memory CD8+ T cell differentia ...... mental program in naïve cells.
@nl
type
label
Memory CD8+ T cell differentia ...... pmental program in naïve cells
@en
Memory CD8+ T cell differentia ...... mental program in naïve cells.
@nl
prefLabel
Memory CD8+ T cell differentia ...... pmental program in naïve cells
@en
Memory CD8+ T cell differentia ...... mental program in naïve cells.
@nl
P2860
P356
P1433
P1476
Memory CD8+ T cell differentia ...... pmental program in naïve cells
@en
P2093
P2860
P304
P356
10.1038/87720
P407
P577
2001-05-01T00:00:00Z