Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes? - Wikidata - wikimedia - TriplyDB

Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

http://www.wikidata.org/entity/Q37141752

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The interplay of autoimmunity and insulin resistance in type 1 diabetes Preclinical rheumatoid arthritis: identification, evaluation, and future directions for investigation An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes.Effects of non-HLA gene polymorphisms on development of islet autoimmunity and type 1 diabetes in a population with high-risk HLA-DR,DQ genotypes.Effect of the PTPN22 and INS risk genotypes on the progression to clinical type 1 diabetes after the initiation of β-cell autoimmunity Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases.HLA-DQ haplotypes differ by ethnicity in patients with childhood-onset diabetes.Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies.The next big idea.Immunotherapy for the prevention and treatment of type 1 diabetes: human trials and a look into the future Emerging treatments for the prevention of type 1 diabetes.The past, present, and future of genetic associations in type 1 diabetes.Influence of type 1 diabetes genes on disease progression: similarities and differences between countries.Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals.Beta-cell specific autoantibodies: Are they just an indicator of type 1 diabetes?Role of immune system modulation in prevention of type 1 diabetes mellitus.rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes Evidence of stage- and age-related heterogeneity of non-HLA SNPs and risk of islet autoimmunity and type 1 diabetes: the diabetes autoimmunity study in the young.Antigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes.PTPN22 gene polymorphism (C1858T) is associated with susceptibility to type 1 diabetes: a meta-analysis of 19,495 cases and 25,341 controls.Genetics of type 1 diabetes Genetic Risk Scores for Type 1 Diabetes Prediction and Diagnosis

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Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

http://www.wikidata.org/entity/Q37141752

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 02 February 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Do non-HLA genes influence dev ...... high-risk HLA-DR,DQ genotypes?

@en

Do non-HLA genes influence dev ...... high-risk HLA-DR,DQ genotypes?

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type

label

Do non-HLA genes influence dev ...... high-risk HLA-DR,DQ genotypes?

@en

Do non-HLA genes influence dev ...... high-risk HLA-DR,DQ genotypes?

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prefLabel

Do non-HLA genes influence dev ...... high-risk HLA-DR,DQ genotypes?

@en

Do non-HLA genes influence dev ...... high-risk HLA-DR,DQ genotypes?

@nl

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Do non-HLA genes influence dev ...... high-risk HLA-DR,DQ genotypes?

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Alan Blair

http://www.w3.org/2001/XMLSchema#string

Andrea K Steck

http://www.w3.org/2001/XMLSchema#string

George S Eisenbarth

http://www.w3.org/2001/XMLSchema#string

Henry A Erlich

http://www.w3.org/2001/XMLSchema#string

Jill M Norris

http://www.w3.org/2001/XMLSchema#string

Katherine J Barriga

http://www.w3.org/2001/XMLSchema#string

Marian J Rewers

http://www.w3.org/2001/XMLSchema#string

Teodorica L Bugawan

http://www.w3.org/2001/XMLSchema#string

Weiming Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status.

Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase.

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1028-1033

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scholarly article

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10.2337/DB08-1179

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58

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2009-02-02T00:00:00Z

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23972536

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19188433

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type-1 diabetes

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2661592

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