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Type 1 diabetes in the BB rat: a polygenic disease

Type 1 diabetes in the BB rat: a polygenic disease

http://www.wikidata.org/entity/Q37141760

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Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo The adverse effects of diabetes on osteoarthritis: update on clinical evidence and molecular mechanisms Experimental Diabetes Mellitus in Different Animal Models Infection with viruses from several families triggers autoimmune diabetes in LEW*1WR1 rats: prevention of diabetes by maternal immunization.A spontaneous animal model of intestinal dysmotility evoked by inflammatory nitrergic dysfunction.T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research.Fine-mapping a locus for glucose tolerance using heterogeneous stock rats Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes.When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases.Biobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes.Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.Identification of a novel gene for diabetic traits in rats, mice, and humans.The use of animal models in diabetes research.Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.Role of the gastrointestinal ecosystem in the development of type 1 diabetes.Different roles of mast cells in obesity and diabetes: lessons from experimental animals and humans.Lipid droplets hypertrophy: a crucial determining factor in insulin regulation by adipocytes.Promotion of autoimmune diabetes by cereal diet in the presence or absence of microbes associated with gut immune activation, regulatory imbalance, and altered cathelicidin antimicrobial Peptide.Concordance of gene expression in human protein complexes reveals tissue specificity and pathology Animal models of diabetic retinopathy: summary and comparison.Virus-induced autoimmune diabetes in the LEW.1WR1 rat requires Iddm14 and a genetic locus proximal to the major histocompatibility complex.Intestinal immune regulation as a potential diet-modifiable feature of gut inflammation and autoimmunity.Relationship between Immunological Abnormalities in Rat Models of Diabetes Mellitus and the Amplification Circuits for Diabetes.Development of the Nonobese Diabetic Mouse and Contribution of Animal Models for Understanding Type 1 Diabetes.Protection against or triggering of Type 1 diabetes? Different roles for viral infections Genetic analysis of type 1 diabetes: embryonic stem cells as new tools to unlock biological mechanisms in type 1 diabetes.The early days of NK cells: an example of how a phenomenon led to detection of a novel immune receptor system - lessons from a rat model β cell ER stress and the implications for immunogenicity in type 1 diabetes.Diabetic aggravation of stroke and animal models.Animal Models of Diabetic Retinopathy Type 1 diabetes genes in rats: few or many?Immunotherapy for the prevention and treatment of type 1 diabetes: optimizing the path from bench to bedside.Redox-Sensitive Innate Immune Pathways During Macrophage Activation in Type 1 Diabetes.Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility.Alx3-deficient mice exhibit decreased insulin in beta cells, altered glucose homeostasis and increased apoptosis in pancreatic islets.Pathogenesis of Type 1 Diabetes Mellitus and Rodent Experimental Models.Genetic dissection of Iddm26 in the spontaneously diabetic BBDP rat

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Type 1 diabetes in the BB rat: a polygenic disease

http://www.wikidata.org/entity/Q37141760

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 23 January 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

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name

Type 1 diabetes in the BB rat: a polygenic disease

@en

Type 1 diabetes in the BB rat: a polygenic disease.

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type

label

Type 1 diabetes in the BB rat: a polygenic disease

@en

Type 1 diabetes in the BB rat: a polygenic disease.

@nl

prefLabel

Type 1 diabetes in the BB rat: a polygenic disease

@en

Type 1 diabetes in the BB rat: a polygenic disease.

@nl

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P1476

Type 1 diabetes in the BB rat: a polygenic disease

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Eugene Hsieh

http://www.w3.org/2001/XMLSchema#string

Gary Y C Chao

http://www.w3.org/2001/XMLSchema#string

Janice Sarmiento

http://www.w3.org/2001/XMLSchema#string

KeSheng Wang

http://www.w3.org/2001/XMLSchema#string

Leili Marandi

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Philippe Poussier

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Robert H Wallis

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Terri Ning

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P2860

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

Cblb is a major susceptibility gene for rat type 1 diabetes mellitus

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1007-1017

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scholarly article

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10.2337/DB08-1215

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4

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58

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Andrew D. Paterson

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2009-01-23T00:00:00Z

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23938911

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19168599

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type-1 diabetes

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2661594

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