Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast) - Wikidata - wikimedia - TriplyDB

Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)

Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)

http://www.wikidata.org/entity/Q37143300

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Addiction science: Uncovering neurobiological complexity Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta Neurobiology of opioid dependence in creating addiction vulnerability Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics Medications development for opioid abuse Glial modulators: a novel pharmacological approach to altering the behavioral effects of abused substances Opioid-induced central immune signaling: implications for opioid analgesia Regulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate Administration Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.Evidence that opioids may have toll-like receptor 4 and MD-2 effects Glial modulators as potential treatments of psychostimulant abuse TLR 2 and 4 responsiveness from isolated peripheral blood mononuclear cells from rats and humans as potential chronic pain biomarkers Activin A is increased in the nucleus accumbens following a cocaine binge The effects of pioglitazone, a PPARγ receptor agonist, on the abuse liability of oxycodone among nondependent opioid users.Neonatal Escherichia coli infection alters glial, cytokine, and neuronal gene expression in response to acute amphetamine in adolescent rats The glial cell modulator and phosphodiesterase inhibitor, AV411 (ibudilast), attenuates prime- and stress-induced methamphetamine relapse.Opioid activation of toll-like receptor 4 contributes to drug reinforcement Development of the Neuroimmune Modulator Ibudilast for the Treatment of Alcoholism: A Randomized, Placebo-Controlled, Human Laboratory Trial.Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae Codeine-induced hyperalgesia and allodynia: investigating the role of glial activation Interactions between the immune and nervous systems in pain.Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia.Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: comparison of different mouse strains Pharmacological induction of CCL5 in vivo prevents gp120-mediated neuronal injury.Current gene therapy using viral vectors for chronic pain Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression.Toll-like receptors in chronic pain.Morphine activates neuroinflammation in a manner parallel to endotoxin The effects of ibudilast, a glial activation inhibitor, on opioid withdrawal symptoms in opioid-dependent volunteers Effects of Acute and Repeated Administration of Oxycodone and Naloxone-Precipitated Withdrawal on Intracranial Self-Stimulation in Rats.Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.Glial cell modulators attenuate methamphetamine self-administration in the rat.Blockade of Toll-like receptor 4 attenuates morphine tolerance and facilitates the pain relieving properties of morphine CCL5 and cytokine expression in the rat brain: differential modulation by chronic morphine and morphine withdrawal.Why is neuroimmunopharmacology crucial for the future of addiction research?BOLD Imaging in Awake Wild-Type and Mu-Opioid Receptor Knock-Out Mice Reveals On-Target Activation Maps in Response to Oxycodone.A double-blind, randomized, placebo-controlled pilot trial to determine the efficacy and safety of ibudilast, a potential glial attenuator, in chronic migraine.

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Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)

http://www.wikidata.org/entity/Q37143300

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 04 October 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Reduction of opioid withdrawal ...... by systemic AV411 (ibudilast)

@en

Reduction of opioid withdrawal ...... id analgesia by systemic AV411

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type

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Reduction of opioid withdrawal ...... by systemic AV411 (ibudilast)

@en

Reduction of opioid withdrawal ...... id analgesia by systemic AV411

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prefLabel

Reduction of opioid withdrawal ...... by systemic AV411 (ibudilast)

@en

Reduction of opioid withdrawal ...... id analgesia by systemic AV411

@nl

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J.BBI.2008.09.012

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Brain, Behavior, and Immunity

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Reduction of opioid withdrawal ...... by systemic AV411 (ibudilast)

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Alexis Northcutt

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Anita Brzeski

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Benjamen D Coats

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Charles M Judd

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Christine M Vietz

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David A Skyba

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Debra L Berkelhammer

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Kirk W Johnson

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Nicole Y Crysdale

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Steven F Maier

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P2860

Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia

Morphine reciprocally regulates IL-10 and IL-12 production by monocyte-derived human dendritic cells and enhances T cell activation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance

A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

Are NMDA receptors involved in opiate-induced neural and behavioral plasticity? A review of preclinical studies.

Drug abuse, dependence, and addiction in chronic pain patients.

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scholarly article

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10.1016/J.BBI.2008.09.012

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2

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Linda R. Watkins

Mark R. Hutchinson

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2008-10-04T00:00:00Z

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