Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants.
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Viral evolution and escape during acute HIV-1 infectionIdentifying Recent HIV Infections: From Serological Assays to GenomicsTissue-resident memory T cellsUsing nonhuman primates to model HIV transmissionOrigin of the transmitted virus in HIV infection: infected cells versus cell-free virusTracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmissionHuman Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus MacaquesExceptional Heterogeneity in Viral Evolutionary Dynamics Characterises Chronic Hepatitis C Virus InfectionClinical significance of HIV-1 coreceptor usage.Bottlenecks in HIV-1 transmission: insights from the study of founder virusesA mathematical framework for estimating pathogen transmission fitness and inoculum size using data from a competitive mixtures animal modelElucidation of hepatitis C virus transmission and early diversification by single genome sequencingDifferences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder VirusHIV-1 infections with multiple founders are associated with higher viral loads than infections with single foundersSurvivors Remorse: antibody-mediated protection against HIV-1.Induction of a Tier-1-like Phenotype in Diverse Tier-2 Isolates by Agents that Guide HIV-1 Env to Perturbation-sensitive, Non-native States.Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants.Vaccine design for CD8 T lymphocyte responsesMucosal transmission of human immunodeficiency virusLimited nucleotide changes in the Rev response element (RRE) during HIV-1 infection alter overall Rev-RRE activity and Rev multimerization.Human immunodeficiency virus vaccine trialsWhole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection.Source identification in two criminal cases using phylogenetic analysis of HIV-1 DNA sequences.An evaluation of phylogenetic methods for reconstructing transmitted HIV variants using longitudinal clonal HIV sequence data.Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection.Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequencesHIV-1 transmitting couples have similar viral load set-points in Rakai, Uganda.High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild.Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.Viral coinfection is shaped by host ecology and virus-virus interactions across diverse microbial taxa and environments.Highly divergent patterns of genetic diversity and evolution in proviral quasispecies from HIV controllers.Recent advances in understanding HIV evolutionHIV-1 vaccine development after STEP.A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays.Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.HIV-1 Populations in Semen Arise through Multiple Mechanisms.Development of replication-competent viral vectors for HIV vaccine delivery.Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.New directions for HIV vaccine development from animal models.
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Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Quantitating the multiplicity ...... ution of transmitted variants.
@en
Quantitating the multiplicity ...... ution of transmitted variants.
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type
label
Quantitating the multiplicity ...... ution of transmitted variants.
@en
Quantitating the multiplicity ...... ution of transmitted variants.
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prefLabel
Quantitating the multiplicity ...... ution of transmitted variants.
@en
Quantitating the multiplicity ...... ution of transmitted variants.
@nl
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Quantitating the multiplicity ...... ution of transmitted variants.
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C Williamson
CAPRISA Acute Infection Study Team
Center for HIV-AIDS Vaccine Immunology Consortium
E E Giorgi
F K Treurnicht
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10.1128/JVI.02132-08
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P577
2009-02-04T00:00:00Z