The role of MRN in the S-phase DNA damage checkpoint is independent of its Ctp1-dependent roles in double-strand break repair and checkpoint signaling.
about
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairMre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint signaling in the S-phase DNA damage checkpointHuman T-lymphotropic type 1 virus p30 inhibits homologous recombination and favors unfaithful DNA repair.Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes.The MRE11 complex: starting from the ends.The fission yeast MRN complex tethers dysfunctional telomeres for NHEJ repairDNA repair in ischemic acute kidney injury.Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast.
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The role of MRN in the S-phase DNA damage checkpoint is independent of its Ctp1-dependent roles in double-strand break repair and checkpoint signaling.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of MRN in the S-phase ...... pair and checkpoint signaling.
@en
The role of MRN in the S-phase ...... pair and checkpoint signaling.
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type
label
The role of MRN in the S-phase ...... pair and checkpoint signaling.
@en
The role of MRN in the S-phase ...... pair and checkpoint signaling.
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prefLabel
The role of MRN in the S-phase ...... pair and checkpoint signaling.
@en
The role of MRN in the S-phase ...... pair and checkpoint signaling.
@nl
P2860
P356
P1476
The role of MRN in the S-phase ...... pair and checkpoint signaling.
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P2093
Mary E Porter-Goff
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P304
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10.1091/MBC.E08-09-0986
P577
2009-02-11T00:00:00Z