Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.
about
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairPhosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae.Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpointRad4 mainly functions in Chk1-mediated DNA damage checkpoint pathway as a scaffold protein in the fission yeast Schizosaccharomyces pombeSae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells - implications from repressive chromatin organization and the role of ARTEMIS.Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.The Rad4(TopBP1) ATR-activation domain functions in G1/S phase in a chromatin-dependent manner.Initiation of DNA damage responses through XPG-related nucleasesAn essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.Critical Function of γH2A in S-PhaseDissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuitBiology of telomeres: lessons from budding yeast.Inner nuclear membrane protein Lem2 facilitates Rad3-mediated checkpoint signaling under replication stress induced by nucleotide depletion in fission yeastATR maintains select progenitors during nervous system development.Hydroxyurea Induces Cytokinesis Arrest in Cells Expressing a Mutated Sterol-14α-Demethylase in the Ergosterol Biosynthesis PathwayActivation of protein kinase Tel1 through recognition of protein-bound DNA endsNonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe.A checkpoint-independent mechanism delays entry into mitosis after UV irradiation.Heme deficiency sensitizes yeast cells to oxidative stress induced by hydroxyurea.Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast.Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1.
P2860
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P2860
Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mre11 nuclease activity and Ct ...... nases at double-strand breaks.
@ast
Mre11 nuclease activity and Ct ...... nases at double-strand breaks.
@en
type
label
Mre11 nuclease activity and Ct ...... nases at double-strand breaks.
@ast
Mre11 nuclease activity and Ct ...... nases at double-strand breaks.
@en
prefLabel
Mre11 nuclease activity and Ct ...... nases at double-strand breaks.
@ast
Mre11 nuclease activity and Ct ...... nases at double-strand breaks.
@en
P2860
P356
P1476
Mre11 nuclease activity and Ct ...... nases at double-strand breaks.
@en
P2093
Mary E Porter-Goff
Paul Russell
P2860
P304
P356
10.1128/MCB.00994-10
P407
P577
2010-11-22T00:00:00Z