Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice
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Animal Models Utilized in HTLV-1 ResearchHeat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia-lymphoma cells.Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo.Animals Models of Human T Cell Leukemia Virus Type I Leukemogenesis.Inhibition of Heat Shock Protein 90 Prevents HIV ReboundEfficiency of AUY922 in mice with adult T-cell leukemia/lymphomaHSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-κB activation and HTLV-1 replicationRegulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Niclosamide, an anti-helminthic molecule, downregulates the retroviral oncoprotein Tax and pro-survival Bcl-2 proteins in HTLV-1-transformed T lymphocytes.Antiobesity and Anti-Inflammatory Effects of Orally Administered Bonito Extracts on Mice Fed a High-Fat Diet.Control of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Eliminating Envelope Protein-Positive Cells with Recombinant Vesicular Stomatitis Viruses Encoding HTLV-1 Primary Receptor.Mouse Models That Enhanced Our Understanding of Adult T Cell Leukemia.Complete Sequences of the Human T-Cell Leukemia Virus Type 1 Proviral Genomes from Newly Established Adult T-Cell Leukemia Cell Lines in Oita Prefecture, Japan.
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Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Oral administration of an HSP9 ...... ival period for ATL model mice
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Oral administration of an HSP9 ...... val period for ATL model mice.
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type
label
Oral administration of an HSP9 ...... ival period for ATL model mice
@en
Oral administration of an HSP9 ...... val period for ATL model mice.
@nl
prefLabel
Oral administration of an HSP9 ...... ival period for ATL model mice
@en
Oral administration of an HSP9 ...... val period for ATL model mice.
@nl
P2093
P2860
P356
P1433
P1476
Oral administration of an HSP9 ...... ival period for ATL model mice
@en
P2093
A Kawaguchi
A Nishizono
H Hasegawa
J Fujisawa
K Morishita
P2860
P2888
P356
10.1038/BCJ.2013.30
P577
2013-08-16T00:00:00Z
P5875
P6179
1001906006