REST is a novel prognostic factor and therapeutic target for medulloblastoma - Wikidata - wikimedia - TriplyDB

REST is a novel prognostic factor and therapeutic target for medulloblastoma

REST is a novel prognostic factor and therapeutic target for medulloblastoma

http://www.wikidata.org/entity/Q37148990

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The REST gene signature predicts drug sensitivity in neuroblastoma cell lines and is significantly associated with neuroblastoma tumor stage.Preclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned?A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease Extensive alternative splicing of the repressor element silencing transcription factor linked to cancer.Downregulation of the Ca(2+)-activated K(+) channel KC a3.1 by histone deacetylase inhibition in human breast cancer cells Signals that regulate the oncogenic fate of neural stem cells and progenitors Neuroprotective effects of psychotropic drugs in Huntington's disease Targeting of histone deacetylases in brain tumors.NRSF: an angel or a devil in neurogenesis and neurological diseases.Medulloblastoma development: tumor biology informs treatment decisions Evolving molecular era of childhood medulloblastoma: time to revisit therapy.The tumor suppressor microRNA, miR-124a, is regulated by epigenetic silencing and by the transcriptional factor, REST in glioblastoma.REST Final-Exon-Truncating Mutations Cause Hereditary Gingival Fibromatosis.Epigenetic regulation in medulloblastoma.REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation.Synergistic anti-cancer effects of epigenetic drugs on medulloblastoma cells.REST, not REST4, is a risk factor associated with radiotherapy plus chemotherapy efficacy in glioma.Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration

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REST is a novel prognostic factor and therapeutic target for medulloblastoma

http://www.wikidata.org/entity/Q37148990

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 30 July 2012

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

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name

REST is a novel prognostic factor and therapeutic target for medulloblastoma

@en

REST is a novel prognostic factor and therapeutic target for medulloblastoma.

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type

label

REST is a novel prognostic factor and therapeutic target for medulloblastoma

@en

REST is a novel prognostic factor and therapeutic target for medulloblastoma.

@nl

prefLabel

REST is a novel prognostic factor and therapeutic target for medulloblastoma

@en

REST is a novel prognostic factor and therapeutic target for medulloblastoma.

@nl

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1535-7163.MCT-11-0990

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Molecular Cancer Therapeutics

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REST is a novel prognostic factor and therapeutic target for medulloblastoma

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P2093

Alvaro Laureano

http://www.w3.org/2001/XMLSchema#string

Irene B Helenowski

http://www.w3.org/2001/XMLSchema#string

Jason Fangusaro

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Laurence Cooper

http://www.w3.org/2001/XMLSchema#string

Pete Taylor

http://www.w3.org/2001/XMLSchema#string

Stewart Goldman

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Tobey MacDonald

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Veena Rajaram

http://www.w3.org/2001/XMLSchema#string

Vidya Gopalakrishnan

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P2860

REST repression of neuronal genes requires components of the hSWI.SNF complex

REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons

The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation

Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

Chromatin crosstalk in development and disease: lessons from REST

Signaling pathways in medulloblastoma.

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1713-1723

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scholarly article

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10.1158/1535-7163.MCT-11-0990

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8

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11

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Martin Hasselblatt

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2012-07-30T00:00:00Z

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230589709

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22848092

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medulloblastoma

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3763747

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