Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism
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Forkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed miceFoxO1 mediates insulin-dependent regulation of hepatic VLDL production in miceProteomic analysis of fructose-induced fatty liver in hamstersCentral nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle.The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD).Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation.Molecular pathways in non-alcoholic fatty liver disease.FoxO1 links hepatic insulin action to endoplasmic reticulum stress.A role of apolipoprotein D in triglyceride metabolismAcute suppression of apo B secretion by insulin occurs independently of MTP.Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule-1 mRNA.Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene.Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis.Wnt signaling regulates hepatic metabolism.FoxO6 integrates insulin signaling with gluconeogenesis in the liver.Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice.FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c.FOXO1 mediates the autocrine effect of endothelin-1 on endothelial cell survival.The new biology of diabetes.Forkhead Box P1 (FOXP1) Transcription Factor Regulates Hepatic Glucose Homeostasis.FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice.FoxO6 in glucose metabolism (FoxO6)Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.ATF4 protein deficiency protects against high fructose-induced hypertriglyceridemia in mice.FoxO1 integrates insulin signaling to VLDL production.PPAR{alpha} mediates the hypolipidemic action of fibrates by antagonizing FoxO1Effect and the probable mechanisms of silibinin in regulating insulin resistance in the liver of rats with non-alcoholic fatty liver.FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages.FoxO6 integrates insulin signaling with MTP for regulating VLDL production in the liver.Forkhead box class O transcription factors in liver function and diseaseA decrease in hepatic microRNA-9 expression impairs gluconeogenesis by targeting FOXO1 in obese mice.Hyperinsulinaemia and insulin signalling in the pathogenesis and the clinical course of hepatocellular carcinoma.Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1cMiR-615-3p inhibits the osteogenic differentiation of human lumbar ligamentum flavum cells via suppression of osteogenic regulators GDF5 and FOXO1.Maf1, A New PTEN Target Linking RNA and Lipid Metabolism.FoxO integration of insulin signaling with glucose and lipid metabolism.Forkhead box class O family member proteins: The biology and pathophysiological roles in diabetes.The constitutive androstane receptor activator 4-[(4R,6R)-4,6-diphenyl-1,3-dioxan-2-yl]-N,N-dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4α and FOXO1 transcriptional activity.FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes.
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Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 September 2006
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism
@en
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism.
@nl
type
label
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism
@en
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism.
@nl
prefLabel
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism
@en
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism.
@nl
P2093
P2860
P50
P356
P1433
P1476
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism
@en
P2093
Adama Kamagate
Marcia Meseck
P2860
P304
P356
10.1210/EN.2006-0541
P407
P577
2006-09-21T00:00:00Z