Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
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Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesisAutophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironmentThe autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolismOxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cellsAn absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancersQuis custodiet ipsos custodies: who watches the watchmen?Molecular pathways: trafficking of metabolic resources in the tumor microenvironmentWounds that will not heal: pervasive cellular reprogramming in cancerIron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesisEthanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer preventionWeak stromal Caveolin-1 expression in colorectal liver metastases predicts poor prognosis after hepatectomy for liver-only colorectal metastases.Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis.Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention?Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells.An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.The role of the microenvironment in mammary gland development and cancer.Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer.Down-regulation of stromal caveolin-1 expression in esophageal squamous cell carcinoma: a potent predictor of lymph node metastases, early tumor recurrence, and poor prognosis.CD271⁺ subpopulation of pancreatic stellate cells correlates with prognosis of pancreatic cancer and is regulated by interaction with cancer cellsLoss of stromal caveolin-1 expression in colorectal cancer predicts poor survivalEvidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator.Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis.Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice.Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connectionAnti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.Caveolin-1 expression is elevated in claudin-low mammary tumor cells.Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysisBreastfeeding and Immunohistochemical Expression of ki-67, p53 and BCL2 in Infiltrating Lobular Breast CarcinomaMolecular characterization of Gleason patterns 3 and 4 prostate cancer using reverse Warburg effect-associated genesCTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drugLow α(2)β(1) integrin function enhances the proliferation of fibroblasts from patients with idiopathic pulmonary fibrosis by activation of the β-catenin pathway.Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glandsBreast Cancer beyond the Age of Mutation.Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.Pregnancy and breast cancer: when they collide.
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Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Caveolin-1-/- null mammary str ...... cancer-associated fibroblasts.
@en
Caveolin-1-/- null mammary str ...... cancer-associated fibroblasts.
@nl
type
label
Caveolin-1-/- null mammary str ...... cancer-associated fibroblasts.
@en
Caveolin-1-/- null mammary str ...... cancer-associated fibroblasts.
@nl
prefLabel
Caveolin-1-/- null mammary str ...... cancer-associated fibroblasts.
@en
Caveolin-1-/- null mammary str ...... cancer-associated fibroblasts.
@nl
P2093
P2860
P50
P1476
Caveolin-1-/- null mammary str ...... cancer-associated fibroblasts.
@en
P2093
Agnieszka K Witkiewicz
Andrew A Quong
Carlo Minetti
Chenguang Wang
Emily Bosco
Erik S Knudsen
Isabelle Mercier
Kristin M Daumer
P2860
P304
P356
10.2353/AJPATH.2009.080658
P407
P50
P577
2009-03-01T00:00:00Z