mRNA splicing variants: exploiting modularity to outwit cancer therapy
about
SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples.Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancerThe role of mRNA splicing in prostate cancer.The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression.Cloning of multiple ERα mRNA variants in killifish (Fundulus heteroclitus), and differential expression by tissue type, stage of reproduction, and estrogen exposure in fish from polluted and unpolluted environments.Alternative RNA structure-coupled gene regulations in tumorigenesis.Test-firing ammunition for spliceosome inhibition in cancer.Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance.Design and synthesis of analogues of natural products.Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma.Modulation of alternative splicing contributes to cancer development: focusing on p53 isoforms, p53β and p53γ.Developing new targeting strategy for androgen receptor variants in castration resistant prostate cancer.The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients.
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mRNA splicing variants: exploiting modularity to outwit cancer therapy
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
mRNA splicing variants: exploiting modularity to outwit cancer therapy
@en
mRNA splicing variants: exploiting modularity to outwit cancer therapy.
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type
label
mRNA splicing variants: exploiting modularity to outwit cancer therapy
@en
mRNA splicing variants: exploiting modularity to outwit cancer therapy.
@nl
prefLabel
mRNA splicing variants: exploiting modularity to outwit cancer therapy
@en
mRNA splicing variants: exploiting modularity to outwit cancer therapy.
@nl
P2860
P1433
P1476
mRNA splicing variants: exploiting modularity to outwit cancer therapy
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P2093
Scott M Dehm
P2860
P304
P356
10.1158/0008-5472.CAN-13-0444
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P577
2013-08-22T00:00:00Z